3,4-Dihydroxyphenylacetic Acid - Metabolism
Research News and Information

Sunday, November 22, 2009

Bee pheromones: signal or agent of manipulation?

26 Jul 2009 Recent studies have provided a new perspective on the relationship between the honey bee queen and her colony. They suggest that the queen produces a pheromone which pharmacologically manipulates her ... Read more...

Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring.

6 Jul 2009 Methamphetamine is a commonly abused psychostimulant that causes addiction and is often abused by pregnant women. Acute or chronic administration of methamphetamine elevates the levels of the extracellular monoamine neurotransmitters, such as ... Read more...

Multiple roles of the active site lysine of Dopa decarboxylase.

2 Jul 2009 The pyridoxal 5'-phosphate dependent-enzyme Dopa decarboxylase, responsible for the irreversible conversion of l-Dopa to dopamine, is an attractive drug target. The contribution of the pyridoxal-Lys303 to the catalytic mechanisms of decarboxylation ... Read more...

Latest indexed articles for '3,4-Dihydroxyphenylacetic Acid - Metabolism'

These are the very latest articles for this heading:

• Bee pheromones: signal or agent of manipulation? 26 Jul 2009
• Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring. 6 Jul 2009
• Multiple roles of the active site lysine of Dopa decarboxylase. 2 Jul 2009
• Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol. 29 Jun 2009
• Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells. 29 Jun 2009
• The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats. 29 Jun 2009
• Dopamine receptor activation by honey bee queen pheromone. 9 Jun 2009
• Developmental vitamin D deficiency alters dopamine turnover in neonatal rat forebrain. 5 Jun 2009
• Whole body hyperthermia reduces oxidative stress in the striatum of rats in an animal model of mitochondrial toxicity with 3-nitropropionic acid. 30 May 2009
• L-DOPA attenuates hyperactivity of Roborovskii hamsters. 29 Apr 2009
• Products of oxidative stress inhibit aldehyde oxidation and reduction pathways in dopamine catabolism yielding elevated levels of a reactive intermediate. 29 Apr 2009
• Learning strategies during fear conditioning. 29 Apr 2009
• Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP. 27 Apr 2009
• Conversion of dehydrodiferulic acids by human intestinal microbiota. 20 Apr 2009
• Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure. 15 Apr 2009
• Acrylamide decreased dopamine levels and increased 3-nitrotyrosine (3-NT) levels in PC 12 cells. 9 Apr 2009
• In vivo dopamine release and uptake impairments in rats treated with 3-nitropropionic acid. 7 Apr 2009
• Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain. 6 Apr 2009
• Chronic treatment with monoamine oxidase-B inhibitors decreases cocaine reward in mice. Apr 2009
• A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats. 26 Mar 2009

See a longer list of these articles.

Technical information about '3,4-Dihydroxyphenylacetic Acid'

Definition: A deaminated metabolite of LEVODOPA.

Chemical name: Benzeneacetic acid, 3,4-dihydroxy-

Registry Number: 102-32-9

Descriptor UI: D015102

Alternative terms: 3,4-Dihydroxyphenylacetic Acid; 3,4 Dihydroxyphenylacetic Acid; DOPAC; Homoprotocatechuic Acid; 3,4-Dihydroxyphenylacetic Acid, Monosodium Salt;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.241.223.601.220;

Online Note: use 3,4-DIHYDROXYPHENYLACETIC ACID to search DOPACETIC ACID 1975-93

History Note: 91(75); was see under PHENYLACETATES 1975-90; DOPACETIC ACID was see 3,4-DIHYDROXYPHENYLACETIC ACID 1975-93