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Acetophenones - Chemistry
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Tuesday, November 24, 2009

CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes.

30 Aug 2009 1. Paeonol, the primary active component of a traditional Chinese medicine Moutan Cortex, has a wide range of pharmacological activities. In the present study, the metabolism of paeonol by cytochrome P450s (CYPs) was investigated in human liver ... Read more...


Azolyacetones as precursors to indoles and naphthofurans facilitated by microwave irradiation with simultaneous cooling.

9 Aug 2009 Phthalimide reacted with phenacyl bromide under microwave irradiation to yield phenacyl isoindolidene-1,3-dione (3b), while 3a reacted with phenylhydrazine to yield the phenylhydrazone 4 that was readily converted into indoylphthalimide 8. Similarly ... Read more...


Iridium/monodentate phosphoramidite catalyzed asymmetric hydrogenation of N-aryl imines.

22 Jun 2009 Asymmetric hydrogenation of N-aryl acetophenone imines using iridium/PipPhos leads to very high enantioselectivities up to >99% depending on the presence of electron-donating substituents in the 2-, 3-, and 5-position of the aryl ring. If the ... Read more...

 

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Technical information about 'Acetophenones'

Registry Number: 0

Descriptor UI: D000098

Alternative terms: Acetophenones;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.522.120;

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