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Acetylcholinesterase - Drug effects
Research News and Information
Definition of 'Acetylcholinesterase'An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7. Common names: Acetylcholinesterase; Acetylcholine Hydrolase; Hydrolase, Acetylcholine; Acetylthiocholinesterase |
Sunday, November 22, 2009
30 Aug 2009 
OBJECTIVES: We have characterised the population pharmacokinetics-pharmacodynamics of pyridostigmine given as pyridostigmine bromide. METHODS: Over three days 50 healthy Chinese male subjects each received seven doses of 30 mg pyridostigmine bromide ... Read more...
11 Aug 2009 The earthworm Eisenia foetida was exposed to different concentrations of imidazolium ionic liquids with varying chain lengths according to the method of OECD [OECD, 1984. (The Current Organization of Economic and Cooperative Development Acute ... Read more...
30 Jul 2009 The green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) was investigated for its enhancement effect of huperzine A on inhibiting acetylcholinesterase (AChE). The inhibitory effect of huperzine A on acetylcholinesterase is quite weak in the ... Read more...
Latest indexed articles for 'Acetylcholinesterase - Drug effects'
These are the very latest articles for this heading:
- Retrospective population pharmacokinetic/pharmacodynamic analysis of pyridostigmine, a cholinesterase inhibitor, in Chinese males. 30 Aug 2009
- The toxic effects of ionic liquids on the activities of acetylcholinesterase and cellulase in earthworms. 11 Aug 2009
- Green tea polyphenol (-)-epigallocatechin-3-gallate enhances the inhibitory effect of huperzine A on acetylcholinesterase by increasing the affinity with serum albumin. 30 Jul 2009
- Cholinesterase inhibitory activities of some flavonoid derivatives and chosen xanthone and their molecular docking studies. 7 Jul 2009
- Acetylcholinesterase inhibitors in MG: to be or not to be? 30 May 2009
- Diphenyl diselenide and streptozotocin did not alter cerebral glutamatergic and cholinergic systems but modulate antioxidant status and sodium pump in diabetic rats. 7 Apr 2009
- Antidepressant-like effect of diphenyl diselenide on rats exposed to malathion: involvement of Na+K+ ATPase activity. 25 Mar 2009
- Study on acetylcholinesterase inhibition induced by endogenous neurotoxin with an enzyme-semiconductor photoelectrochemical system. 24 Mar 2009
- 3-Fluoro-2,4-dioxa-3-phosphadecalins as inhibitors of acetylcholinesterase. A reappraisal of kinetic mechanisms and diagnostic methods. 27 Feb 2009
- Effects of cholinesterase inhibition on brain white matter volume in Alzheimer's disease. 16 Feb 2009
- Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits. 3 Feb 2009
- New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors. 30 Jan 2009
- Clinical limitations of acetylcholinesterase antagonists. 15 Jan 2009
- Inhibition of acetylcholinesterase by metabolites of copper pyrithione (CuPT) and its possible involvement in vertebral deformity of a CuPT-exposed marine teleostean fish. 11 Jan 2009
- Different inhibition of acetylcholinesterase in selected parts of the rat brain following intoxication with VX and Russian VX. 30 Dec 2008
- Rapid method for measurement of acetylcholinesterase activity. 30 Dec 2008
- Progress of biosensors based on cholinesterase inhibition. 30 Dec 2008
- Effect of concurrent application of heat, swim stress and repeated dermal application of chlorpyrifos on the hippocampal neurons in mice.
30 Dec 2008 - Biochemical and behavioral effects of diazinon exposure in hybrid striped bass. 30 Dec 2008
- Cholinergic stimulation improves autonomic and hemodynamic profile during dynamic exercise in patients with heart failure. 30 Nov 2008
See a longer list of these articles.
Technical information about 'Acetylcholinesterase'
Definition: An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
Chemical name: Acetylcholine acetylhydrolase
Registry Number: EC 3.1.1.7
Descriptor UI: D000110
Alternative terms: Acetylcholinesterase; Acetylcholine Hydrolase; Hydrolase, Acetylcholine; Acetylthiocholinesterase;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;
Tree Number: D08.811.277.352.100.170.176;
Technical Notes: reactivation or reactivators: coord NIM (with no qualif) with CHOLINESTERASE REACTIVATORS (IM)