Adenine - Chemistry
Research News and Information

Sunday, November 22, 2009

Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study.

30 Aug 2009 Piano stool ruthenium complexes of the composition [Ru(II)(eta6-arene)(en)Cl](+/2+) (en = ethylenediamine) represent an emerging class of cisplatin-analogue anticancer drug candidates. In this study, we use computational quantum chemistry to ... Read more...

Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB.

9 Aug 2009 Promiscuous substrate recognition, the ability to catalyze transformations of chemically diverse compounds, is an evolutionarily advantageous, but poorly understood phenomenon. The promiscuity of DNA repair enzymes is particularly important, because ... Read more...

Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair.

9 Aug 2009 Inflammation-mediated reactive molecules can damage DNA by oxidation and chlorination. The biological consequences of this damage are as yet incompletely understood. In this paper, we have constructed oligonucleotides containing 5-chlorouracil ... Read more...

Latest indexed articles for 'Adenine - Chemistry'

These are the very latest articles for this heading:

• Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study. 30 Aug 2009
• Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB. 9 Aug 2009
• Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair. 9 Aug 2009
• Intramolecular triple helix as a model for regular polyribonucleotide (CAA)(n). 28 Jul 2009
• An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases. 27 Jul 2009
• MD simulations of ligand-bound and ligand-free aptamer: molecular level insights into the binding and switching mechanism of the add A-riboswitch. 20 Jul 2009
• Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90. 19 Jul 2009
• Fingerprints of bonding motifs in DNA duplexes of adenine and thymine revealed from circular dichroism: synchrotron radiation experiments and TDDFT calculations. 14 Jul 2009
• The structure of the protonated adenine dimer by infrared multiple photon dissociation spectroscopy and electronic structure calculations. 14 Jul 2009
• Effects of hydration on the proton transfer mechanism in the adenine-thymine base pair. 7 Jul 2009
• The role of adenine in fast excited-state deactivation of FAD: a femtosecond mid-IR transient absorption study. 7 Jul 2009
• Ultraviolet photostability of adenine on gold and silicon surfaces. 29 Jun 2009
• SERS detection of low-concentration adenine by a patterned silver structure immersion plated on a silicon nanoporous pillar array. 29 Jun 2009
• UNA (unlocked nucleic acid): a flexible RNA mimic that allows engineering of nucleic acid duplex stability. 25 Jun 2009
• Cation-triggered drug release from a porous zinc-adeninate metal-organic framework. 22 Jun 2009
• A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops. 21 Jun 2009
• Improved phosphoramidite building blocks for the synthesis of the simplified nucleic acid GNA. 17 Jun 2009
• Hydrogen bonding between adenine-modified surfaces and terminal thymine-functionalized polystyrene: influence of the surface adenine concentration on polymer recognition. 14 Jun 2009
• Classification and energetics of the base-phosphate interactions in RNA. 12 Jun 2009
• Self-assembling sequence-adaptive peptide nucleic acids. 9 Jun 2009

See a longer list of these articles.

Technical information about 'Adenine'

Definition: A purine base and a fundamental unit of ADENINE NUCLEOTIDES.

Chemical name: 1H-Purin-6-amine

Registry Number: 73-24-5

Descriptor UI: D000225

Alternative terms: Adenine; Vitamin B 4; 4, Vitamin B; B 4, Vitamin;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis; physiology;

Tree Number: D03.438.759.138;

Technical Notes: /biosyn/physiol permitted