Adenylate Cyclase - Genetics
Research News and Information

Sunday, November 22, 2009

Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning.

28 Sep 2009 Dopamine (DA)-dependent corticostriatal plasticity is thought to underlie incremental procedural learning. A primary effector of striatal DA signaling is cAMP, yet its role in corticostriatal plasticity and striatum-dependent learning remains ... Read more...

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

2 Sep 2009 Adenylyl cyclase (AC) types 5 and 6 (AC5 and AC6) are the two major AC isoforms expressed in the mammalian heart that mediate signals from beta-adrenergic receptor stimulation. Because of the unavailability of isoform-specific antibodies, it is ... Read more...

Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice.

31 Aug 2009 Hippocampus-dependent memory requires a cAMP signal that is generated by Ca2+-stimulated adenylyl cyclases (AC1, AC8). Young transgenic mice overexpressing AC1 in the forebrain (AC1+ mice) have enhanced hippocampal long-term potentiation, superior ... Read more...

Latest indexed articles for 'Adenylate Cyclase - Genetics'

These are the very latest articles for this heading:

• Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. 28 Sep 2009
• Adenylyl cyclase type 5 protein expression during cardiac development and stress. 2 Sep 2009
• Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice. 31 Aug 2009
• Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors. 18 Aug 2009
• Persistent cAMP-signals triggered by internalized G-protein-coupled receptors. 16 Aug 2009
• Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. 9 Aug 2009
• Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase. Aug 2009
• An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes. 29 Jun 2009
• Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans. 29 Jun 2009
• Ethanol-modulated camouflage response screen in zebrafish uncovers a novel role for cAMP and extracellular signal-regulated kinase signaling in behavioral sensitivity to ethanol. 29 Jun 2009
• Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation. 29 Jun 2009
• Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6. 24 Jun 2009
• Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase. 8 Jun 2009
• Differential inhibition of various adenylyl cyclase isoforms and soluble guanylyl cyclase by 2',3'-O-(2,4,6-trinitrophenyl)-substituted nucleoside 5'-triphosphates. Jun 2009
• cAMP signaling in Mycobacterium tuberculosis. 30 May 2009
• Involvement of a membrane-bound class III adenylate cyclase in regulation of anaerobic respiration in Shewanella oneidensis MR-1. 22 Apr 2009
• Global regulators orchestrate group II intron retromobility. 22 Apr 2009
• Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. 21 Apr 2009
• Use-dependent plasticity in clock neurons regulates sleep need in Drosophila. Apr 2009
• Characterization of mouse heart adenylyl cyclase. 21 Mar 2009

See a longer list of these articles.

Technical information about 'Adenylate Cyclase'

Definition: An enzyme of the lyase class that catalyzes the formation of CYCLIC AMP and pyrophosphate from ATP. EC 4.6.1.1.

Chemical name: ATP pyrophosphate-lyase (cyclizing)

Registry Number: EC 4.6.1.1

Descriptor UI: D000262

Alternative terms: Adenylate Cyclase; Cyclase, Adenylate; Adenylyl Cyclase; Cyclase, Adenylyl; Adenyl Cyclase; Cyclase, Adenyl;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.520.650.200; D12.644.360.050; D12.776.476.050;

History Note: 98(68)