Adenylate Cyclase - Metabolism
Research News and Information

Monday, November 23, 2009

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

2 Sep 2009 Adenylyl cyclase (AC) types 5 and 6 (AC5 and AC6) are the two major AC isoforms expressed in the mammalian heart that mediate signals from beta-adrenergic receptor stimulation. Because of the unavailability of isoform-specific antibodies, it is ... Read more...

Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase.

30 Aug 2009 Parathyroid hormone (PTH) regulates bone remodeling and calcium and phosphate homeostasis. PTH actions are mediated by type I PTH/PTH-related peptide receptor (PTH1R). There has been no commercially available, specific antibody to detect human PTH1R ... Read more...

Mu opioid receptor from the zebrafish exhibits functional characteristics as those of mammalian mu opioid receptor.

30 Aug 2009 The functional characterization of the mu opioid receptor from the zebrafish (zfMOR) is reported here. After transfection in HEK-293 cell line, using both peptidergic and nonpeptidergic opioid ligands in the competition and saturation-binding ... Read more...

Latest indexed articles for 'Adenylate Cyclase - Metabolism'

These are the very latest articles for this heading:

• Adenylyl cyclase type 5 protein expression during cardiac development and stress. 2 Sep 2009
• Generation of human PTH1R construct with FLAG epitope located internally: comparison of two-fragment assembly by using PCR overlap extension or ligase. 30 Aug 2009
• Mu opioid receptor from the zebrafish exhibits functional characteristics as those of mammalian mu opioid receptor. 30 Aug 2009
• Vasoactive intestinal peptide acts via multiple signal pathways to regulate hippocampal NMDA receptors and synaptic transmission. 30 Aug 2009
• Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors. 18 Aug 2009
• Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption. 17 Aug 2009
• Persistent cAMP-signals triggered by internalized G-protein-coupled receptors. 16 Aug 2009
• Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. 9 Aug 2009
• Nucleotide regulation of soluble guanylate cyclase substrate specificity. 9 Aug 2009
• Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase. Aug 2009
• Possible mechanism of CCL2-induced Akt activation in prostate cancer cells. 30 Jul 2009
• Nitric oxide dilates rat retinal blood vessels by cyclooxygenase-dependent mechanisms. 20 Jul 2009
• Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae. 14 Jul 2009
• Resistin regulates pituitary somatotrope cell function through the activation of multiple signaling pathways. 7 Jul 2009
• Adenylate cyclase regulates elongation of mammalian primary cilia. 30 Jun 2009
• An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes. 29 Jun 2009
• cAMP-dependent chloride conductance evokes ammonia-induced blebbing in the microglial cell line, BV-2. 29 Jun 2009
• Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans. 29 Jun 2009
• Ethanol-modulated camouflage response screen in zebrafish uncovers a novel role for cAMP and extracellular signal-regulated kinase signaling in behavioral sensitivity to ethanol. 29 Jun 2009
• Phosphodiesterase inhibition by naloxone augments the inotropic actions of beta-adrenergic stimulation. 28 Jun 2009

See a longer list of these articles.

Technical information about 'Adenylate Cyclase'

Definition: An enzyme of the lyase class that catalyzes the formation of CYCLIC AMP and pyrophosphate from ATP. EC 4.6.1.1.

Chemical name: ATP pyrophosphate-lyase (cyclizing)

Registry Number: EC 4.6.1.1

Descriptor UI: D000262

Alternative terms: Adenylate Cyclase; Cyclase, Adenylate; Adenylyl Cyclase; Cyclase, Adenylyl; Adenyl Cyclase; Cyclase, Adenyl;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.520.650.200; D12.644.360.050; D12.776.476.050;

History Note: 98(68)