Adiponectin - Research News and Information

Wednesday, January 07, 2009

Nonalcoholic fatty liver disease, adiponectin and insulin resistance in dipper and nondipper essential hypertensive patients.

30 Oct 2008 OBJECTIVE: The pathogenesis of nonalcoholic fatty liver disease (NAFLD) is multifactorial, and the presence of insulin resistance is recognized as the pathophysiological hallmark of this condition. Arterial hypertension is referred as an ... Read more...

Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism.

30 Oct 2008 There is controversy regarding whether fructose in liquid beverages constitutes another dietary ingredient of high caloric density or introduces qualitative changes in energy metabolism that further facilitate the appearance of metabolic diseases. ... Read more...

The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.

7 Oct 2008 Adiponectin is an adipocyte-derived cytokine that has attracted much attention because of its insulin-sensitizing effects in liver and skeletal muscle. Two adiponectin receptors, AdipoR1/R2, have been cloned, but relatively little is known about ... Read more...

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Latest indexed articles for 'Adiponectin'

These are the very latest articles for this heading:

• Nonalcoholic fatty liver disease, adiponectin and insulin resistance in dipper and nondipper essential hypertensive patients. 30 Oct 2008
• Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism. 30 Oct 2008
• The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth. 7 Oct 2008
• Circulating levels of adiponectin and leptin at 23-25 weeks of pregnancy in women with impaired placentation and in those with established fetal growth restriction. 29 Sep 2008
• Relationship between serum adiponectin and prostate cancer grade. 29 Sep 2008
• Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. 29 Sep 2008
• Does the hormone of eternal youth protect against nonalcoholic steatohepatitis? 29 Sep 2008
• Involvement of low adiponectin levels in impaired glucose tolerance. 29 Sep 2008
• Effects of telmisartan on adiponectin levels and body weight in hypertensive patients with glucose intolerance. 29 Sep 2008
• Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cells. 29 Sep 2008
• Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. 29 Sep 2008
• The effects of BADGE and caffeine on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis. 29 Sep 2008
• Adiponectin differentially affects gene expression in human mammary epithelial and breast cancer cells. 28 Sep 2008
• Prediagnostic adiponectin concentrations and pancreatic cancer risk in male smokers. 16 Sep 2008
• Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. 10 Sep 2008
• Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression. 10 Sep 2008
• Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, E3030, in db/db mice and beagle dogs. 4 Sep 2008
• Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. 31 Aug 2008
• Importance of the high-molecular-mass isoform of adiponectin in improved insulin sensitivity with rosiglitazone treatment in HIV disease. 30 Aug 2008
• Effects of losartan on serum total and high-molecular weight adiponectin concentrations in hypertensive patients with metabolic syndrome. 30 Aug 2008

See a longer list of these articles.

Technical information about 'Adiponectin'

Definition: A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the white ADIPOSE TISSUE. Adiponectin modulates several physiological processes, such as metabolism of GLUCOSE and FATTY ACIDS, and immune responses. Decreased plasma adiponectin levels are associated with INSULIN RESISTANCE; TYPE 2 DIABETES MELLITUS; OBESITY; and ATHEROSCLEROSIS.

Registry Number: 0

Descriptor UI: D052242

Alternative terms: Adiponectin; Adipocyte Complement-Related Protein 30-kDa; Adipocyte Complement Related Protein 30 kDa; Adipose Most Abundant Gene Transcript 1; apM-1 Protein; apM 1 Protein; ACRP30 Protein; Adipocyte, C1q and Collagen Domain Containing Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D06.472.699.042.249; D12.644.276.024.249; D12.644.548.011.249; D12.776.467.024.249; D23.529.024.249;

History Note: 2006 (1996)