Administration, Cutaneous - Research News and Information

Wednesday, January 07, 2009

Microneedle-based drug delivery: studies on delivery parameters and biocompatibility.

29 Sep 2008 There is a significant interest in the application of microneedles in intradermal drug delivery systems. Previous studies have demonstrated that skin permeation of drugs can be increased by orders of magnitude with microneedle insertion. In this ... Read more...

Synthesis of piperazinylalkyl ester prodrugs of ketorolac and their in vitro evaluation for transdermal delivery.

29 Sep 2008 Ketorolac, an NSAID, has low intrinsic permeation capacity through the skin. In this work, seven piperazinylalkyl ester prodrugs of ketorolac were synthesized to enhance its skin permeation. The chemical hydrolysis and the stability in human serum ... Read more...

Effect of adhesive matrix composition and terpinolene on indomethacin bioavailability in rats from transdermal therapeutic system.

29 Sep 2008 Drug-in-adhesive matrix-type transdermal therapeutic systems for indomethacin (IND) were formulated and evaluated. Silicone and two types of polyacrylates were used as the bases of matrices. Terpinolene was used as a penetration enhancer. The ... Read more...

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Latest indexed articles for 'Administration, Cutaneous'

These are the very latest articles for this heading:

• Re: randomized controlled trial to evaluate transdermal testosterone in female cancer survivors with decreased libido: north central cancer treatment group protocol N02C3. 5 Oct 2008
• Microneedle-based drug delivery: studies on delivery parameters and biocompatibility. 29 Sep 2008
• Synthesis of piperazinylalkyl ester prodrugs of ketorolac and their in vitro evaluation for transdermal delivery. 29 Sep 2008
• Effect of adhesive matrix composition and terpinolene on indomethacin bioavailability in rats from transdermal therapeutic system. 29 Sep 2008
• Clinical inquiries: how does VTE risk for the patch and vaginal ring compare with oral contraceptives? 29 Sep 2008
• Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice. 29 Sep 2008
• Design and evaluation of chitosan films for transdermal delivery of glimepiride. 29 Sep 2008
• [Development of a transcutaneous vaccination system using a hydrogel patch] 29 Sep 2008
• [Skin vaccination] 29 Sep 2008
• Is Australia headed for an epidemic of nicotine replacement therapy addicts? 13 Sep 2008
• Characterization of monolithic matrix patch system containing tulobuterol. 10 Sep 2008
• A new scalp formulation of calcipotriene plus betamethasone compared with its active ingredients and the vehicle in the treatment of scalp psoriasis: a randomized, double-blind, controlled trial. 30 Aug 2008
• Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders. 30 Aug 2008
• Over-the-counter nicotine replacement therapy: a methodological review of the evidence supporting its effectiveness. 30 Aug 2008
• Enhanced controlled release of loratadine from the ethylene-vinyl acetate matrix containing plasticizer. 30 Aug 2008
• Optimization of iontophoretic parameters for the transdermal delivery of methotrexate. 30 Aug 2008
• Transdermal delivery of carvedilol containing glycyrrhizin and chitosan as permeation enhancers: biochemical, biophysical, microscopic and pharmacodynamic evaluation. 30 Aug 2008
• In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug. 30 Aug 2008
• Nicotine and postoperative management of pain. 30 Aug 2008
• Transdermal nicotine for analgesia after radical retropubic prostatectomy. 30 Aug 2008

See a longer list of these articles.

Technical information about 'Administration, Cutaneous'

Definition: The application of suitable drug dosage forms to the skin for either local or systemic effects.

Descriptor UI: D000279

Alternative terms: Administration, Cutaneous; Administration, Dermal; Administrations, Dermal; Dermal Administrations; Dermal Administration; Cutaneous Administration; Administrations, Cutaneous; Cutaneous Administrations; Skin Administration, Drug; Drug Skin Administrations; Skin Administrations, Drug; Drug Administration, Cutaneous; Administration, Cutaneous Drug; Administrations, Cutaneous Drug; Cutaneous Drug Administrations; Drug Administrations, Cutaneous; Cutaneous Drug Administration; Dermal Drug Administration; Administration, Dermal Drug; Administrations, Dermal Drug; Dermal Drug Administrations; Drug Administrations, Dermal; Drug Administration, Dermal; Skin Drug Administration; Skin Drug Administrations; Cutaneous Administration, Drug; Cutaneous Administrations, Drug; Administration, Transcutaneous; Administrations, Transcutaneous; Transcutaneous Administrations; Administration, Transdermal; Administrations, Transdermal; Transdermal Administrations; Transdermal Administration; Transcutaneous Administration; Percutaneous Administration; Administration, Percutaneous; Administrations, Percutaneous; Percutaneous Administrations;

Related Mesh Headings: Skin Absorption;

Tree Number: E02.319.267.120.060;

History Note: 87

Technical Notes: NIM but only if discussed: do not index here routinely for every cutaneously administered drug; no qualif