Adrenergic Agents
Research News and Information

Saturday, November 21, 2009

Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors.

30 Oct 2009 The dopamine D4 receptor (D4R) is predominantly expressed in the prefrontal cortex, a brain area that integrates motor, rewarding, and cognitive information. Because participation of D4Rs in executive learning is largely unknown, we challenged D4R ... Read more...

Serotonin 1B receptor stimulation reduces D1 receptor agonist-induced dyskinesia.

21 Sep 2009 Dopamine replacement therapy for the treatment of Parkinson's disease leads to deleterious abnormal involuntary movements (AIMs), known as L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia, which parallels enhanced striatal dopamine D1 ... Read more...

Direct excitation of spinal GABAergic interneurons by noradrenaline.

13 Jul 2009 Endogenous pain control is, in part, mediated by descending inhibition of spinal nociception via spinal release of noradrenaline. Antinociception by activation of descending noradrenergic fibres has partially been attributed to the direct inhibition ... Read more...

Latest indexed articles for 'Adrenergic Agents'

These are the very latest articles for this heading:

• Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors. 30 Oct 2009
• Serotonin 1B receptor stimulation reduces D1 receptor agonist-induced dyskinesia. 21 Sep 2009
• Pulse contour analysis aids the understanding of autonomic dysreflexia: hemodynamic findings in a T5 paraplegic surgical patient treated for hypotension with phenylephrine and ephedrine. 20 Aug 2009
• Direct excitation of spinal GABAergic interneurons by noradrenaline. 13 Jul 2009
• Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. 29 Jun 2009
• Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. 26 Jun 2009
• Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease. 23 Jun 2009
• Parallel synthesis of potent dopaminergic N-phenyltriazole carboxamides applying a novel click chemistry based phenol linker. 23 Jun 2009
• Effects of dopamine depletion on network entropy in the external globus pallidus. 15 Jun 2009
• Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons. 15 Jun 2009
• Autonomic regulation of blood pressure in menopause. 13 Jun 2009
• Amphetamine-evoked rotation requires newly synthesized dopamine at 14 days but not 1 day after intranigral 6-OHDA and is consistently dissociated from sensorimotor behavior. 6 Jun 2009
• Effects of amphetamine on salivary secretion. 30 May 2009
• Pharmacotherapy for the obese patient. 30 May 2009
• Dopamine depletion induces distinct compensatory gene expression changes in DARPP-32 signal transduction cascades of striatonigral and striatopallidal neurons. 25 May 2009
• Mesolimbic alpha-, but not beta-adrenoceptors control the accumbal release of dopamine that is derived from reserpine-sensitive storage vesicles. 19 May 2009
• A role for medial prefrontal dopaminergic innervation in instrumental conditioning. 18 May 2009
• Temperature sensitivity of cardiac function in pelagic fishes with different vertical mobilities: yellowfin tuna (Thunnus albacares), bigeye tuna (Thunnus obesus), mahimahi (Coryphaena hippurus), and swordfish (Xiphias gladius). 29 Apr 2009
• Brain oxidative stress and selective behaviour of aluminium in specific areas of rat brain: potential effects in a 6-OHDA-induced model of Parkinson's disease. 29 Apr 2009
• Extracellular dopamine and norepinephrine in the developing rat prefrontal cortex: transient effects of early partial loss of dopamine. 27 Apr 2009

See a longer list of these articles.

Technical information about 'Adrenergic Agents'

Definition: Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.

Registry Number: 0

Descriptor UI: D018663

Alternative terms: Adrenergic Agents; Agents, Adrenergic; Adrenergics; Adrenergic Drugs; Drugs, Adrenergic; Sympathetic Transmitter Releasers; Releasers, Sympathetic Transmitter; Transmitter Releasers, Sympathetic; Adrenergic Release Inhibitors; Inhibitors, Adrenergic Release; Release Inhibitors, Adrenergic; Adrenergic Synthesis Inhibitors; Inhibitors, Adrenergic Synthesis; Synthesis Inhibitors, Adrenergic; Adrenergic Neurohumor Depleters; Depleters, Adrenergic Neurohumor; Neurohumor Depleters, Adrenergic; Adrenergic Neuron Agents; Agents, Adrenergic Neuron; Neuron Agents, Adrenergic; Adrenergic Neuron Drugs; Drugs, Adrenergic Neuron; Neuron Drugs, Adrenergic;

Related Mesh Headings: Sympatholytics; Sympathomimetics;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Tree Number: D27.505.519.625.050; D27.505.696.577.050;

Online Note: use SYMPATHOMIMETICS to search SYMPATHETIC TRANSMITTER RELEASERS 1976-94, ADRENERGIC AGENTS 1977-94 & ADRENOMIMETICS 1975-94; use SYMPATHOLYTICS to search ADRENOLYTICS 1975-94

History Note: 95; was see SYMPATHOMIMETICS 1977-94; ADRENERGIC NEURON AGENTS was heading 1995; ADRENERGIC NEUROHUMOR DEPLETERS, ADRENERGIC RELEASE INHIBITORS, ADRENERGIC SYNTHESIS INHIBITORS, & SYMPATHETIC TRANSMITTER RELEASERS were see ADRENERGIC NEURON AGENTS 1995; SYMPATHETIC TRANSMITTER RELEASERS was see SYMPATHOMIMETICS 1976-94; ADRENOLYTICS was see SYMPATHOLYTICS 1975-94; ADRENOMIMETICS was see SYMPATHOMIMETICS 1975-94

Technical Notes: DF: ADREN AGENTS