Aging - Genetics
Research News and Information

Sunday, November 22, 2009

Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes.

5 Oct 2009 Senescence-accelerated prone (SAMP) strain 8 mice suffer an earlier development of cognitive age-related pathologies and a shorter life span than conventional mice. Protein alterations in astrocytes, in addition to those in neurons, may contribute ... Read more...

Is there more to aging than mitochondrial DNA and reactive oxygen species?

29 Sep 2009 With the aging of the population, we are seeing a global increase in the prevalence of age-related disorders, especially in developed countries. Chronic diseases disproportionately affect the older segment of the population, contributing to ... Read more...

Not all quiet on the noise front.

29 Sep 2009 Phenotypic diversity exists even within isogenic populations of cells. Such nongenetic individuality may have wide implications for our understanding of many biological processes. The field of study concerned with the investigation of nongenetic ... Read more...

Latest indexed articles for 'Aging - Genetics'

These are the very latest articles for this heading:

• DNA damage, aging, and cancer. 6 Oct 2009
• Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes. 5 Oct 2009
• Is there more to aging than mitochondrial DNA and reactive oxygen species? 29 Sep 2009
• Not all quiet on the noise front. 29 Sep 2009
• [The transcription of the amyloid precursor protein and tryptophan 2,3-dioxygenase genes are increased by aging in the rat brain] 28 Sep 2009
• The effect of replication initiation on gene amplification in the rDNA and its relationship to aging. 9 Sep 2009
• Does HUMARA assay for assessment of clonal hematopoiesis have shortcomings? 8 Sep 2009
• Can we intervene in human ageing? 5 Sep 2009
• Ageing-related chromatin defects through loss of the NURD complex. 4 Sep 2009
• Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice. 31 Aug 2009
• Microarray evaluation of age-related changes in human dental pulp. 30 Aug 2009
• A crucial role for adipose tissue p53 in the regulation of insulin resistance. 28 Aug 2009
• A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. 26 Aug 2009
• [Early signs of ageing and the importance of lifecourse factors for the aging process] 22 Aug 2009
• Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? 17 Aug 2009
• Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. 12 Aug 2009
• Genetic (Co)variation for life span in rhabditid nematodes: role of mutation, selection, and history. 9 Aug 2009
• Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice. 2 Aug 2009
• Werner syndrome resembles normal aging. 30 Jul 2009
• Effects of age on segregation of the X and Y chromosomes in cultured lymphocytes from Chinese men. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Aging'

Definition: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Descriptor UI: D000375

Alternative terms: Aging; Senescence; Biological Aging; Aging, Biological;

Related Mesh Headings: Skin Aging; Cell Aging;

Allowable Qualifiers: blood; cerebrospinal fluid; drug effects; ethnology; genetics; immunology; metabolism; physiology; psychology; radiation effects; urine; ethics; pathology;

Tree Number: G07.700.320.124;

Technical Notes: human & animal; IM; aging process anywhere between birth & old age; differentiation from other age-related terms: Manual 28.16, 34.10; "aging" of lower organisms, cultures, drugs, etc. is probably TIME FACTORS; AGING, PREMATURE is also available