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Aging - Physiology
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Definition of 'Aging'

The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Common names: Aging; Senescence; Biological Aging; Aging, Biological

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Saturday, November 21, 2009

Clinical outcome after 450 revascularization procedures for moyamoya disease. Clinical article.

30 Oct 2009 OBJECT: Moyamoya disease (MMD) is a rare cerebrovascular disease mainly described in the Asian literature. To address a lack of data on clinical characteristics and long-term outcomes in the treatment of MMD in North America, the authors analyzed ... Read more...


Immune activation in brain aging and neurodegeneration: too much or too little?

13 Oct 2009 Until recently, the brain was studied almost exclusively by neuroscientists and the immune system by immunologists, fuelling the notion that these systems represented two isolated entities. However, as more data suggest an important role of the ... Read more...


Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation.

10 Oct 2009 Mutations in the neuronal protein alpha-synuclein cause familial Parkinson disease. Phosphorylation of alpha-synuclein at serine 129 is prominent in Parkinson disease and influences alpha-synuclein neurotoxicity. Here we report that alpha-synuclein ... Read more...

 

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Technical information about 'Aging'

Definition: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Descriptor UI: D000375

Alternative terms: Aging; Senescence; Biological Aging; Aging, Biological;

Related Mesh Headings: Skin Aging; Cell Aging;

Allowable Qualifiers: blood; cerebrospinal fluid; drug effects; ethnology; genetics; immunology; metabolism; physiology; psychology; radiation effects; urine; ethics; pathology;

Tree Number: G07.700.320.124;

Technical Notes: human & animal; IM; aging process anywhere between birth & old age; differentiation from other age-related terms: Manual 28.16, 34.10; "aging" of lower organisms, cultures, drugs, etc. is probably TIME FACTORS; AGING, PREMATURE is also available

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