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Aging - Research News and Information

Wednesday, January 07, 2009

Definition of 'Aging'

The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Common names: Aging; Senescence; Biological Aging; Aging, Biological

More technical Information...

Preneoplastic and neoplastic lesions in the lung, liver and urinary tract of mice exposed to environmental cigarette smoke and UV light since birth.

29 Nov 2008 It is difficult to reproduce the carcinogenicity of cigarette smoke (CS) in animal models. Recently, we showed that exposure of mice to mainstream CS (MCS) for 120 days, starting immediately after birth, resulted in an early and potent carcinogenic ... Read more...


Age and pattern of the onset of differential growth among growth plates in rats.

30 Oct 2008 Differential growth is the phenomenon whereby growth plates in the same individual at the same time all have uniquely different axial growth velocities. Differential growth is clearly present in the adolescent skeleton. In this study we ask two ... Read more...


Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.

30 Oct 2008 Advanced age is a major risk factor for atherosclerosis, but how aging per se influences pathogenesis is not clear. Insulin-like growth factor-1 receptor (IGF-1R) promotes aortic vascular smooth muscle cell (VSMC) growth, migration, and ... Read more...

 

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Technical information about 'Aging'

Definition: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Descriptor UI: D000375

Alternative terms: Aging; Senescence; Biological Aging; Aging, Biological;

Related Mesh Headings: Skin Aging; Cell Aging;

Allowable Qualifiers: blood; cerebrospinal fluid; drug effects; ethnology; genetics; immunology; metabolism; physiology; psychology; radiation effects; urine; ethics; pathology;

Tree Number: G07.700.320.124;

Technical Notes: human & animal; IM; aging process anywhere between birth & old age; differentiation from other age-related terms: Manual 28.16, 34.10; "aging" of lower organisms, cultures, drugs, etc. is probably TIME FACTORS; AGING, PREMATURE is also available

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