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AIDS Dementia Complex - Diagnosis
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Definition of 'AIDS Dementia Complex'

A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

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Sunday, November 22, 2009

Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain.

30 Aug 2009 OBJECTIVE: HIV enters the brain soon after infection causing neuronal damage and microglial/astrocyte dysfunction leading to neuropsychological impairment. We examined the impact of HIV on resting cerebral blood flow (rCBF) within the lenticular ... Read more...


HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda.

30 Aug 2009 BACKGROUND: In the United States, clade B is the predominant human immunodeficiency virus (HIV) subtype, whereas in sub-Saharan Africa, clades A, C, and D are the predominant subtypes. HIV subtype may have an impact on HIV disease progression. The ... Read more...


High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS.

28 Jul 2009 Highly active antiretroviral treatment (HAART) has had a significant impact on survival of individuals with acquired immunodeficiency syndrome (AIDS); however, with the longer life-span of patients with AIDS, there is increasing prevalence of AIDS ... Read more...

 

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Technical information about 'AIDS Dementia Complex'

Definition: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Descriptor UI: D015526

Alternative terms: AIDS Dementia Complex; Complex, AIDS Dementia; Dementia Complex, AIDS; AIDS-Related Dementia Complex; AIDS Related Dementia Complex; HIV-Associated Cognitive Motor Complex; HIV Associated Cognitive Motor Complex; Dementia Complex, AIDS-Related; Complex, AIDS-Related Dementia; Dementia Complex, AIDS Related; HIV Dementia; Dementia, HIV; Dementias, HIV; HIV Dementias; Acquired-Immune Deficiency Syndrome Dementia Complex; Dementia Complex, Acquired Immune Deficiency Syndrome; HIV-1-Associated Cognitive Motor Complex; HIV 1 Associated Cognitive Motor Complex; HIV-1 Cognitive and Motor Complex; HIV 1 Cognitive and Motor Complex; HIV Encephalopathy; Encephalopathies, HIV; HIV Encephalopathies; Encephalopathy, HIV; AIDS Encephalopathy; AIDS Encephalopathies; Encephalopathies, AIDS; Encephalopathy, AIDS;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; transmission; urine; veterinary; ultrasonography; virology;

Tree Number: C02.782.815.616.400.070; C02.800.801.400.070; C10.228.140.380.070; C20.673.480.070; F03.087.400.050;

History Note: 1990

Technical Notes: coord IM with HIV-1 or HIV-2 (IM or NIM) if pertinent

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