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AIDS Dementia Complex - Epidemiology
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Definition of 'AIDS Dementia Complex'

A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

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Sunday, November 22, 2009

HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda.

30 Aug 2009 BACKGROUND: In the United States, clade B is the predominant human immunodeficiency virus (HIV) subtype, whereas in sub-Saharan Africa, clades A, C, and D are the predominant subtypes. HIV subtype may have an impact on HIV disease progression. The ... Read more...


Closing gaps in antiretroviral therapy access: human immunodeficiency virus-associated dementia screening instruments for non-physician healthcare workers.

30 May 2009 Human immunodeficiency virus-associated dementia (HIV-D) is an indication for antiretroviral therapy (ART), but HIV-D is not routinely screened for in ART clinics in sub-Saharan Africa. Given the dearth of physicians in sub-Saharan Africa, enabling ... Read more...


The International HIV Dementia Scale is a useful screening tool for HIV-associated dementia/cognitive impairment in HIV-infected adults in Yaoundé-Cameroon.

29 Nov 2008 OBJECTIVE: As a baseline for a series of studies on HIV-associated dementia (HAD), we sought to assess the usefulness of the recently developed International HIV Dementia Scale (IHDS) as a screening tool for HAD or HIV-associated cognitive ... Read more...

 

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Technical information about 'AIDS Dementia Complex'

Definition: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Descriptor UI: D015526

Alternative terms: AIDS Dementia Complex; Complex, AIDS Dementia; Dementia Complex, AIDS; AIDS-Related Dementia Complex; AIDS Related Dementia Complex; HIV-Associated Cognitive Motor Complex; HIV Associated Cognitive Motor Complex; Dementia Complex, AIDS-Related; Complex, AIDS-Related Dementia; Dementia Complex, AIDS Related; HIV Dementia; Dementia, HIV; Dementias, HIV; HIV Dementias; Acquired-Immune Deficiency Syndrome Dementia Complex; Dementia Complex, Acquired Immune Deficiency Syndrome; HIV-1-Associated Cognitive Motor Complex; HIV 1 Associated Cognitive Motor Complex; HIV-1 Cognitive and Motor Complex; HIV 1 Cognitive and Motor Complex; HIV Encephalopathy; Encephalopathies, HIV; HIV Encephalopathies; Encephalopathy, HIV; AIDS Encephalopathy; AIDS Encephalopathies; Encephalopathies, AIDS; Encephalopathy, AIDS;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; transmission; urine; veterinary; ultrasonography; virology;

Tree Number: C02.782.815.616.400.070; C02.800.801.400.070; C10.228.140.380.070; C20.673.480.070; F03.087.400.050;

History Note: 1990

Technical Notes: coord IM with HIV-1 or HIV-2 (IM or NIM) if pertinent

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