AIDS Dementia Complex
Research News and Information

Monday, November 23, 2009

A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.

13 Oct 2009 The use of antiretroviral therapy has reduced mortality and increased the quality of life of HIV-1-infected people, particularly in more developed countries where access to treatment is more widespread. However, morbidities continue, which include ... Read more...

Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain.

30 Aug 2009 OBJECTIVE: HIV enters the brain soon after infection causing neuronal damage and microglial/astrocyte dysfunction leading to neuropsychological impairment. We examined the impact of HIV on resting cerebral blood flow (rCBF) within the lenticular ... Read more...

HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda.

30 Aug 2009 BACKGROUND: In the United States, clade B is the predominant human immunodeficiency virus (HIV) subtype, whereas in sub-Saharan Africa, clades A, C, and D are the predominant subtypes. HIV subtype may have an impact on HIV disease progression. The ... Read more...

Latest indexed articles for 'AIDS Dementia Complex'

These are the very latest articles for this heading:

• A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection. 13 Oct 2009
• Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain. 30 Aug 2009
• HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda. 30 Aug 2009
• Parkinsonism in hiv-infected patients on highly active antiretroviral therapy. 2 Aug 2009
• Comparative study of CSF neurofilaments in HTLV-1-associated myelopathy/tropical spastic paraparesis and other neurological disorders. 30 Jul 2009
• Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia. 30 Jul 2009
• Human immunodeficiency virus encephalopathy: cognitive and radiologic improvement after antiretroviral therapy. 30 Jul 2009
• High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS. 28 Jul 2009
• NanoART, neuroAIDS and CNS drug delivery. 29 Jun 2009
• HIV-associated brain dysfunction in the era of HAART: reasons for hope, but continued concern. 22 Jun 2009
• Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders. 19 Jun 2009
• The role of alcohol on platelets, thymus and cognitive performance among HIV-infected subjects: are they related? 30 May 2009
• HIV-1 associated dementia: update on pathological mechanisms and therapeutic approaches. 30 May 2009
• Closing gaps in antiretroviral therapy access: human immunodeficiency virus-associated dementia screening instruments for non-physician healthcare workers. 30 May 2009
• Functional consequences of HIV-associated neuropsychological impairment. 25 May 2009
• Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy. 25 May 2009
• 4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis. 21 May 2009
• Cognitive neuropsychology of HIV-associated neurocognitive disorders. 20 May 2009
• Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008. 18 May 2009
• Impairments in memory and hippocampal function in HIV-positive vs HIV-negative women: a preliminary study. 10 May 2009

See a longer list of these articles.

Technical information about 'AIDS Dementia Complex'

Definition: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Descriptor UI: D015526

Alternative terms: AIDS Dementia Complex; Complex, AIDS Dementia; Dementia Complex, AIDS; AIDS-Related Dementia Complex; AIDS Related Dementia Complex; HIV-Associated Cognitive Motor Complex; HIV Associated Cognitive Motor Complex; Dementia Complex, AIDS-Related; Complex, AIDS-Related Dementia; Dementia Complex, AIDS Related; HIV Dementia; Dementia, HIV; Dementias, HIV; HIV Dementias; Acquired-Immune Deficiency Syndrome Dementia Complex; Dementia Complex, Acquired Immune Deficiency Syndrome; HIV-1-Associated Cognitive Motor Complex; HIV 1 Associated Cognitive Motor Complex; HIV-1 Cognitive and Motor Complex; HIV 1 Cognitive and Motor Complex; HIV Encephalopathy; Encephalopathies, HIV; HIV Encephalopathies; Encephalopathy, HIV; AIDS Encephalopathy; AIDS Encephalopathies; Encephalopathies, AIDS; Encephalopathy, AIDS;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; transmission; urine; veterinary; ultrasonography; virology;

Tree Number: C02.782.815.616.400.070; C02.800.801.400.070; C10.228.140.380.070; C20.673.480.070; F03.087.400.050;

History Note: 1990

Technical Notes: coord IM with HIV-1 or HIV-2 (IM or NIM) if pertinent