Aldehyde Dehydrogenase
Research News and Information

Sunday, November 22, 2009

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.

25 Sep 2009 The location of embryonic lymph node development is determined by the initial clustering of lymphoid tissue-inducer (LTi) cells. Here we demonstrate that both the chemokine CXCL13 and the chemokine CCL21 attracted LTi cells at embryonic days ... Read more...

ALDH2, ADH1B and alcohol expectancies: integrating genetic and learning perspectives.

30 Aug 2009 The present study evaluated associations of ALDH2 and ADH1B genotypes with alcohol expectancies and drinking behavior in a sample of Asian American young adults. In addition to assessing global alcohol expectancies, the authors developed a measure ... Read more...

Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis.

30 Aug 2009 Genetic variants in alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) genes modulate acetaldehyde removal upon alcohol ingestion. Although these genetic vulnerabilities have been linked to higher esophageal squamous cell ... Read more...

Latest indexed articles for 'Aldehyde Dehydrogenase'

These are the very latest articles for this heading:

• Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. 25 Sep 2009
• ALDH2, ADH1B and alcohol expectancies: integrating genetic and learning perspectives. 30 Aug 2009
• Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis. 30 Aug 2009
• Preventive effects of Chlorella on cognitive decline in age-dependent dementia model mice. 19 Aug 2009
• Interaction of the effects of alcohol drinking and polymorphisms in alcohol-metabolizing enzymes on the risk of female breast cancer in Japan. 6 Aug 2009
• Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: implications for retinoid balance in gonad development. 30 Jul 2009
• Pharmacokinetic and pharmacodynamic basis for overcoming acetaldehyde-induced adverse reaction in Asian alcoholics, heterozygous for the variant ALDH2*2 gene allele. 30 Jul 2009
• Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers. 29 Jul 2009
• Synthesis of some novel organic nitrates and comparative in vitro study of their vasodilator profile. 7 Jul 2009
• Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag. 4 Jul 2009
• Salivary aldehyde dehydrogenase: activity towards aromatic aldehydes and comparison with recombinant ALDH3A1. 30 Jun 2009
• Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4. 29 Jun 2009
• Bone marrow-derived aldehyde dehydrogenase-bright stem and progenitor cells for ischemic repair. 29 Jun 2009
• Tempol reduces the therapeutic effect of cyclophosphamide on an experimental tumour model. 29 Jun 2009
• Four flavonoids from Echinosophora koreensis and their effects on alcohol metabolizing enzymes. 24 Jun 2009
• Lag-phase autophagy in the methylotrophic yeast Pichia pastoris. 20 Jun 2009
• Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model. 19 Jun 2009
• The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer. 10 Jun 2009
• Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. 7 Jun 2009
• Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2. 6 Jun 2009

See a longer list of these articles.

Technical information about 'Aldehyde Dehydrogenase'

Definition: An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.

Chemical name: Aldehyde:NAD+ oxidoreductase

Registry Number: EC 1.2.1.3

Descriptor UI: D000444

Alternative terms: Aldehyde Dehydrogenase; Dehydrogenase, Aldehyde; D-Glucuronolactone Dehydrogenase; D Glucuronolactone Dehydrogenase; Dehydrogenase, D-Glucuronolactone; Aldehyde Dehydrogenase (NAD(+)); Aldehyde-NAD Oxidoreductase; Aldehyde NAD Oxidoreductase; Aldehyde Dehydrogenase E2; Aldehyde Dehydrogenase E1;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.682.657.163.249;

History Note: 85