Alkaloids - Toxicity
Research News and Information

Monday, November 23, 2009

Nicotinic plant poisoning.

30 Aug 2009 INTRODUCTION: A wide range of plants contain nicotinic and nicotinic-like alkaloids. Of this diverse group, those that have been reported to cause human poisoning appear to have similar mechanisms of toxicity and presenting patients therefore have ... Read more...

Structure-analgesic activity relationship studies on the C(18)- and C(19)-diterpenoid alkaloids.

30 Jul 2009 For evaluation of C(18)- and C(19)-diterpenoid alkaloids as analgesics, three C(19)-diterpenoid alkaloids were isolated from the roots of Aconitum hemsleyanum var. circinatum and A. transsecutum; and twenty-five semisynthetic C(18)- or ... Read more...

Changes in Lupinus albus and Lupinus angustifolius alkaloid profiles in response to mechanical damage.

20 Jul 2009 The aim of this work was to evaluate chemical responses to biomass removal mimicking large herbivore action in Lupinus albus and Lupinus angustifolius aerial parts. GC and GC-MS were used to determine total alkaloid content (TAC) and alkaloid ... Read more...

Latest indexed articles for 'Alkaloids - Toxicity'

These are the very latest articles for this heading:

• Nicotinic plant poisoning. 30 Aug 2009
• Structure-analgesic activity relationship studies on the C(18)- and C(19)-diterpenoid alkaloids. 30 Jul 2009
• Changes in Lupinus albus and Lupinus angustifolius alkaloid profiles in response to mechanical damage. 20 Jul 2009
• The biogeographical distribution of duncecap larkspur (Delphinium occidentale) chemotypes and their potential toxicity. 19 May 2009
• Outbreak of salivary syndrome on several horse farms in the Netherlands. 7 May 2009
• Effects of larkspur (Delphinium barbeyi) on heart rate and electrically evoked electromyographic response of the external anal sphincter in cattle. 30 Mar 2009
• A metabolomic analysis of the toxicity of Aconitum sp. alkaloids in rats using gas chromatography/mass spectrometry. 30 Mar 2009
• Studies on protein characteristics and toxic constituents of Simarouba glauca oilseed meal. 11 Mar 2009
• HPLC-MS analysis of toxic norditerpenoid alkaloids: refinement of toxicity assessment of low larkspurs (Delphinium spp.). 27 Feb 2009
• The alkaloid profiles of Lupinus sulphureus. 23 Feb 2009
• Detoxification of gramine by the cereal aphid Sitobion avenae. 16 Feb 2009
• Safety evaluation of Trikatu, a generic Ayurvedic medicine in Charles Foster rats. 30 Jan 2009
• Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines. 30 Jan 2009
• Effect of argemone oil and argemone alkaloid, sanguinarine on Sertoli-germ cell coculture. 14 Jan 2009
• Alkaloids toxic to livestock. 30 Dec 2008
• Antimalarial natural products of marine and freshwater origin. 30 Dec 2008
• Multidrug and toxic compound extrusion-type transporters implicated in vacuolar sequestration of nicotine in tobacco roots. 17 Dec 2008
• Gramine-induced growth inhibition, oxidative damage and antioxidant responses in freshwater cyanobacterium Microcystis aeruginosa. 25 Nov 2008
• Evaluation of the mutagenic effects of myosmine in human lymphocytes using the HPRT gene mutation assay. 11 Nov 2008
• Effects of strictosamide on mouse brain and kidney Na+, K+-ATPase and Mg2+-ATPase activities. 30 Oct 2008

See a longer list of these articles.

Technical information about 'Alkaloids'

Definition: Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)

Registry Number: 0

Descriptor UI: D000470

Alternative terms: Alkaloids;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.132;

Technical Notes: GEN or unspecified; prefer specific groups or specific alkaloid; alkaloids from specific plants go here (IM) + name of plant or PLANTS, MEDICINAL, etc.