Alkaloids
Research News and Information

Sunday, November 22, 2009

Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts.

29 Nov 2009 The receptor activator of nuclear factor-kappaB ligand (RANKL) plays a critical role in the differentiation and bone resorptive activity of osteoclasts. Recently, the development of anti-resorptive agents from natural substances has become a subject ... Read more...

Antibacterial activity of synthetic fire ant venom: the solenopsins and isosolenopsins.

29 Sep 2009 BACKGROUND: We determined the in vitro activity of 9 synthetic fire ant venom alkaloids (+/-)-solenopsin A, (2R, 6R)-solenopsin A, (2S, 6S)-solenopsin B, (+/-)-isosolenopsin A, (2S, 6R)-isosolenopsin A,(2R, 6S)-isosolenopsin A, (+/-)-isosolenopsin ... Read more...

Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay.

24 Sep 2009 Acetylcholinesterase inhibitors (AChEIs) currently form the basis of the newest drugs available for the treatment of Alzheimer's disease. For the aim of screening effective AChEIs, the methanol extracts of the seeds of genus Peganum were found to ... Read more...

Latest indexed articles for 'Alkaloids'

These are the very latest articles for this heading:

• Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts. 29 Nov 2009
• Antibacterial activity of synthetic fire ant venom: the solenopsins and isosolenopsins. 29 Sep 2009
• Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay. 24 Sep 2009
• Chemical constituents from the leaves of Ilex paraguariensis inhibit human neutrophil elastase. 24 Sep 2009
• Asymmetric aldol reaction of acetaldehyde and isatin derivatives for the total syntheses of ent-convolutamydine E and CPC-1 and a half fragment of madindoline A and B. Sep 2009
• Total synthesis of brevisamide. Sep 2009
• Gene regulation of alpha4beta2 nicotinic receptors: microarray analysis of nicotine-induced receptor up-regulation and anti-inflammatory effects. 30 Aug 2009
• Novel pepper extract for enhanced P-glycoprotein inhibition. 30 Aug 2009
• Bioactive guanidine alkaloids from two Caribbean marine sponges. 30 Aug 2009
• Alkaloids from the leaves of Daphniphyllum subverticillatum. 30 Aug 2009
• Pandanus alkaloids in Stemonaceae: finding of a plausible biogenetic origin of Stemona alkaloids. 30 Aug 2009
• Parazoanthines A-E, hydantoin alkaloids from the Mediterranean sea anemone Parazoanthus axinellae. 30 Aug 2009
• Cerebrosides of the halotolerant fungus Alternaria raphani isolated from a sea salt field. 30 Aug 2009
• Nicotinic plant poisoning. 30 Aug 2009
• Trigonelline is a novel phytoestrogen in coffee beans. 24 Aug 2009
• Access to a welwitindolinone core using sequential cycloadditions. 18 Aug 2009
• Total synthesis of (+)-lyconadin A and related compounds via oxidative C-N bond formation. 10 Aug 2009
• Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn. 10 Aug 2009
• Stereocontrolled cyclic nitrone cycloaddition strategy for the synthesis of pyrrolizidine and indolizidine alkaloids. 8 Aug 2009
• Fifty years of chemical research at Farmitalia. 8 Aug 2009

See a longer list of these articles.

Technical information about 'Alkaloids'

Definition: Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)

Registry Number: 0

Descriptor UI: D000470

Alternative terms: Alkaloids;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.132;

Technical Notes: GEN or unspecified; prefer specific groups or specific alkaloid; alkaloids from specific plants go here (IM) + name of plant or PLANTS, MEDICINAL, etc.