Alleles
Research News and Information

Sunday, November 22, 2009

Fanconi anemia and biallelic BRCA2 mutation diagnosed in a young child with an embryonal CNS tumor.

29 Nov 2009 Medulloblastoma, the most common pediatric malignant brain tumor often arises sporadically; however, in a subgroup of patients, there exist familial conditions such as Fanconi anemia with biallelic BRCA2 mutation that predispose patients to ... Read more...

Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in Helicobacter pylori-infected Peruvians.

30 Oct 2009 Particular alleles of the interleukin-1B (IL-1B) gene have been correlated with increased risk of atrophic gastritis and gastric cancer in the populations of East Asia and Europe. No such data exist from Peru, a developing country with a population ... Read more...

CDK4 IVS4-nt40G-->A and T2D-associated obesity in Italians.

30 Oct 2009 Cell cycle regulators play crucial roles in the preadipocyte proliferation and adipocyte differentiation. Cyclin-dependent kinase 4 (CDK4) mediates with D-type cyclins entry of cells into cell cycle in response to external stimuli. CDK4 plays a role ... Read more...

Latest indexed articles for 'Alleles'

These are the very latest articles for this heading:

• Novel multiple, monoallelic KRAS mutations at codon 12 and 13. 29 Nov 2009
• Fanconi anemia and biallelic BRCA2 mutation diagnosed in a young child with an embryonal CNS tumor. 29 Nov 2009
• Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in Helicobacter pylori-infected Peruvians. 30 Oct 2009
• CDK4 IVS4-nt40G-->A and T2D-associated obesity in Italians. 30 Oct 2009
• Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms. 30 Oct 2009
• Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes. 21 Oct 2009
• Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study. 21 Oct 2009
• A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. 17 Oct 2009
• Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting. 13 Oct 2009
• Genetic susceptibility to rheumatoid arthritis: an emerging picture. 13 Oct 2009
• Allelic inactivation of rDNA loci. 13 Oct 2009
• Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03). 13 Oct 2009
• Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice. 10 Oct 2009
• Clonality and allelotype analyses of focal nodular hyperplasia compared with hepatocellular adenoma and carcinoma. 5 Oct 2009
• Patterns of colonization and spread in the fungal spruce pathogen Onnia tomentosa. 3 Oct 2009
• Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae. 30 Sep 2009
• Understanding the basis for the association of apoE4 with Alzheimer's disease: opening the door for therapeutic approaches. 29 Sep 2009
• Phenylalanine 4-monooxygenase and the role of endobiotic metabolism enzymes in xenobiotic biotransformation. 29 Sep 2009
• A common haplotype of the LBP gene predisposes to severe sepsis. 29 Sep 2009
• Is it time for intensivists to learn genomics? 29 Sep 2009

See a longer list of these articles.

Technical information about 'Alleles'

Definition: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.

Descriptor UI: D000483

Alternative terms: Alleles; Allele; Allelomorphs; Allelomorph;

Tree Number: G05.360.340.024.340.030;

History Note: 68