Alleles - Research News and Information

Wednesday, January 07, 2009

Polymorphisms of fibroblast growth factor receptor 4 have association with the development of prostate cancer and benign prostatic hyperplasia and the progression of prostate cancer in a Japanese population.

29 Nov 2008 Fibroblast growth factor receptor 4 (FGFR4) is a member of a family of transmembrane receptors with ligand-induced tyrosine kinase activity. The Glycine (Gly) to Arginine (Arg) polymorphism at codon 388 (Gly388Arg), which encodes an amino acid in ... Read more...

Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage.

30 Oct 2008 Functional inactivation of the pRb-dependent pathway is a general feature of human cancer. However, only a reduced spectrum of tumors displays inactivation of the Rb gene. This can be attributed, at least partially, to the possible overlapping ... Read more...

Phenotype/genotype correlations in a DFNB1 cohort with ethnical diversity.

30 Oct 2008 OBJECTIVES/HYPOTHESIS: The aim of this study was to 1) determine the prevalence of DFNB1 in a cohort of children with prelingual nonsyndromic sensorineural hearing loss (HL), 2) study phenotype/genotype correlations, and 3) establish guidelines for ... Read more...

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Latest indexed articles for 'Alleles'

These are the very latest articles for this heading:

• Polymorphisms of fibroblast growth factor receptor 4 have association with the development of prostate cancer and benign prostatic hyperplasia and the progression of prostate cancer in a Japanese population. 29 Nov 2008
• Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage. 30 Oct 2008
• Phenotype/genotype correlations in a DFNB1 cohort with ethnical diversity. 30 Oct 2008
• The effects of stress and APOE genotype on cognition in older adults. 30 Oct 2008
• Association of serotonin transporter gene polymorphisms with poststroke depression. 30 Oct 2008
• Child abuse and adult major depression: no evidence of protective gene. 30 Oct 2008
• Analysis of major alleles associated with age-related macular degeneration in patients with multifocal choroiditis: strong association with complement factor H. 30 Oct 2008
• Re: HLA-DRB1 and multiple sclerosis in Malta. 19 Oct 2008
• PrimerSNP: a web tool for whole-genome selection of allele-specific and common primers of phylogenetically-related bacterial genomic sequences. 18 Oct 2008
• Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele. 15 Oct 2008
• Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. 15 Oct 2008
• Activating mutations in ALK provide a therapeutic target in neuroblastoma. 14 Oct 2008
• Comment on "Molecular basis of the dual functions of 2B4 (CD244)". 13 Oct 2008
• HLA-E: strong association with beta2-microglobulin and surface expression in the absence of HLA class I signal sequence-derived peptides. 13 Oct 2008
• A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis. 13 Oct 2008
• A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 13 Oct 2008
• Genetic hitchhiking can promote the initial spread of strong altruism. 8 Oct 2008
• Rapid screening of Salmonella enterica serovars Enteritidis, Hadar, Heidelberg and Typhimurium using a serologically-correlative allelotyping PCR targeting the O and H antigen alleles. 7 Oct 2008
• APOE epsilon4 allele is associated with cognitive impairment in patients with multiple sclerosis. 5 Oct 2008
• The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae. 5 Oct 2008

See a longer list of these articles.

Technical information about 'Alleles'

Definition: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.

Descriptor UI: D000483

Alternative terms: Alleles; Allele; Allelomorphs; Allelomorph;

Tree Number: G05.360.340.024.340.030;

History Note: 68