Allergens - Immunology
Research News and Information

Saturday, November 21, 2009

The human skin/chick chorioallantoic membrane model accurately predicts the potency of cosmetic allergens.

21 Oct 2009 The current standard method for predicting contact allergenicity is the murine local lymph node assay (LLNA). Public objection to the use of animals in testing of cosmetics makes the development of a system that does not use sentient animals highly ... Read more...

Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor.

10 Oct 2009 Of the potent lipid inflammatory mediators comprising the cysteinyl leukotrienes (LTs; LTC4, LTD4, and LTE4), only LTE4 is stable and abundant in vivo. Although LTE4 shows negligible activity at the type 1 and 2 receptors for cys-LTs (CysLT1R and ... Read more...

Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge.

29 Sep 2009 BACKGROUND: Allergen-specific IgE antibodies are responsible for the pathogenesis of type I hypersensitivity. In patients with allergy, IgE titers can persist in the apparent absence of allergen for years. Seasonal allergen exposure triggers ... Read more...

Latest indexed articles for 'Allergens - Immunology'

These are the very latest articles for this heading:

• The human skin/chick chorioallantoic membrane model accurately predicts the potency of cosmetic allergens. 21 Oct 2009
• Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor. 10 Oct 2009
• Discovering anaphylaxis: Elucidation of a shocking phenomenon. 29 Sep 2009
• Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge. 29 Sep 2009
• Does exposure to cats and dogs decrease the risk of allergic sensitization and disease? 29 Sep 2009
• Anaphylaxis syndromes related to a new mammalian cross-reactive carbohydrate determinant. 29 Sep 2009
• Mechanisms of mast cell signaling in anaphylaxis. 29 Sep 2009
• Anaphylaxis: Recent advances in assessment and treatment. 29 Sep 2009
• Mitochondrial dysfunction increases allergic airway inflammation. 26 Sep 2009
• Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. 26 Sep 2009
• Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17. 23 Sep 2009
• Enhanced Th2 cell differentiation and allergen-induced airway inflammation in Zfp35-deficient mice. 23 Sep 2009
• Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. 23 Sep 2009
• Associations between prenatal pesticide exposure and cough, wheeze, and IgE in early childhood. 17 Sep 2009
• Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma. 17 Sep 2009
• Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis. 17 Sep 2009
• Recommendations for appropriate sublingual immunotherapy clinical trials. 17 Sep 2009
• Changes in weather and the effects on pediatric asthma exacerbations. 30 Aug 2009
• Scotch broom, Cytisus scoparius. 30 Aug 2009
• Relationship between myopia and allergen-specific serum IgE levels in patients with allergic conjunctivitis. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Allergens'

Definition: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Registry Number: 0

Descriptor UI: D000485

Alternative terms: Allergens;

Related Mesh Headings: Bites and Stings; Dust; Feathers; Fungi;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; pharmacokinetics;

Tree Number: D23.050.063;

History Note: 65

Technical Notes: coord IM with specific allergen (IM), e.g., pollen as an allergen = ALLERGENS + POLLEN