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alpha 1-Antitrypsin Deficiency - Complications
Research News and Information
Definition of 'alpha 1-Antitrypsin Deficiency'Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN, leading primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. (From Scriver, Beaudet, Sly, & Valle, The Metabolic and Molecular Bases of Inherited Disease, 7th ed, p4125) Common names: alpha 1-Antitrypsin Deficiency; Deficiencies, alpha 1-Antitrypsin; Deficiency, alpha 1-Antitrypsin; alpha 1 Antitrypsin Deficiency; alpha 1-Antitrypsin Deficiencies |
Sunday, November 22, 2009
Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency.
31 Aug 2009 
Alpha-1-antitrypsin deficiency is a genetic condition associated with severe, early-onset chronic obstructive pulmonary disease (COPD). However, there is significant variability in lung function impairment among persons with the protease inhibitor ... Read more...
Genetics of COPD and emphysema.
30 Aug 2009 COPD is a highly prevalent disorder that results from the interplay of genetic susceptibility and environmental exposures. Over the past 2 decades, significant technological advances have been made in genetic investigations of complex diseases, yet ... Read more...
Hepatocellular carcinoma--epidemiological trends and risk factors.
20 Jun 2009 Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide with about 600,000 patients dying from the disease annually. In 70-90%, HCC develops on the background of chronic liver cirrhosis or inflammation. Risk ... Read more...
Latest indexed articles for 'alpha 1-Antitrypsin Deficiency - Complications'
These are the very latest articles for this heading:
- [Genetics in chronic obstructive pulmonary disease]
20 Oct 2009 - Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency. 31 Aug 2009
- Genetics of COPD and emphysema. 30 Aug 2009
- Intravenous alpha1-antitrypsin in a child with deficiency and severe lung disease. 29 Jun 2009
- Clinical practice. Alpha1-antitrypsin deficiency. 23 Jun 2009
- Hepatocellular carcinoma--epidemiological trends and risk factors. 20 Jun 2009
- [Alpha-1-antitrypsin deficiency: diagnosis and therapy of the lung disease] 8 Jun 2009
- [Mortality analysis of patients undergoing lung transplantation for emphysema]
18 May 2009 - Lung volume reduction surgery for patients with alpha-1 antitrypsin deficiency emphysema. 29 Apr 2009
- Screening for Alpha 1 antitrypsin deficiency in Tunisian subjects with obstructive lung disease: a feasibility report. 13 Apr 2009
- Alfa-1-antitrypsin deficiency panniculitis acquired after liver transplant and successfully treated with retransplant. 30 Mar 2009
- Completely asymptomatic proximal aortic dissection and massive bullous lung disease: coincidence or is there any etiologic link? 26 Mar 2009
- Pneumothorax associated with alpha1-antitrypsin deficiency. 28 Feb 2009
- Alpha1-antitrypsin deficiency: lessons from longevity. 27 Feb 2009
- New Findings in PiZZ alpha1-antitrypsin deficiency-related panniculitis. Demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy. 14 Feb 2009
- Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency. 30 Jan 2009
- Effects of a disease management program in individuals with alpha-1 antitrypsin deficiency. 30 Jan 2009
- Physician alert suggesting alpha-1 antitrypsin deficiency testing in pulmonary function test (PFT) results. 30 Jan 2009
- Endoscopic treatment of gastroesophageal varices in young infants with cyanoacrylate glue: a pilot study. 16 Jan 2009
- Long-term augmentation therapy with alpha-1 antitrypsin in an MZ-AAT severe persistent asthma. 29 Nov 2008
See a longer list of these articles.
Technical information about 'alpha 1-Antitrypsin Deficiency'
Definition: Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN, leading primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. (From Scriver, Beaudet, Sly, & Valle, The Metabolic and Molecular Bases of Inherited Disease, 7th ed, p4125)
Descriptor UI: D019896
Alternative terms: alpha 1-Antitrypsin Deficiency; Deficiencies, alpha 1-Antitrypsin; Deficiency, alpha 1-Antitrypsin; alpha 1 Antitrypsin Deficiency; alpha 1-Antitrypsin Deficiencies;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C17.300.050;
History Note: 98
Technical Notes: Pi or PiZZ goes here + PHENOTYPE; DF: ALPHA 1 ANTITRYPSIN DEFIC