Alu Elements - Genetics
Research News and Information

Tuesday, November 24, 2009

Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer.

30 Jul 2009 Hypomethylation of DNA repetitive elements is a common finding in cancer, but very little is known about the DNA methylation changes of different types of DNA repetitive elements, such as interspersed repeats (LINE1 and Alu Yb8) and tandem repeats ... Read more...

Differential repetitive DNA methylation in multiple myeloma molecular subgroups.

14 Jun 2009 Multiple myeloma (MM) is characterized by a wide spectrum of genetic changes. Global hypomethylation of repetitive genomic sequences such as long interspersed nuclear element 1 (LINE-1), Alu and satellite alpha (SAT-alpha) sequences has been ... Read more...

Single particle adsorbing transfer system.

30 May 2009 Here we present a novel approach for horizontal transfer of single particles after laser microdissection. The developed technique is a single particle adsorbing system for highly selective and gentle horizontal transfer of microdissected fixed and ... Read more...

Latest indexed articles for 'Alu Elements - Genetics'

These are the very latest articles for this heading:

• Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer. 30 Jul 2009
• Differential repetitive DNA methylation in multiple myeloma molecular subgroups. 14 Jun 2009
• Single particle adsorbing transfer system. 30 May 2009
• Comparative analysis of Alu repeats in primate genomes. 29 Apr 2009
• Alu-Alu recombination underlies the vast majority of large VHL germline deletions: Molecular characterization and genotype-phenotype correlations in VHL patients. 29 Apr 2009
• Disease-causing mutations improving the branch site and polypyrimidine tract: pseudoexon activation of LINE-2 and antisense Alu lacking the poly(T)-tail. 29 Apr 2009
• A novel Alu-mediated Xq28 microdeletion ablates TAZ and partially deletes DNL1L in a patient with Barth syndrome. 29 Apr 2009
• Chromosomal study of native and hatchery trouts from Italy (Salmo trutta complex, Salmonidae): conventional and FISH analysis. 13 Apr 2009
• The association between HLA-A, -B alleles and major histocompatibility complex class I polymorphic Alu insertions in four populations in China. 4 Apr 2009
• Outline of a genome navigation system based on the properties of GA-sequences and their flanks. 7 Mar 2009
• Diverse cis factors controlling Alu retrotransposition: what causes Alu elements to die? 7 Mar 2009
• [Analysis of Alu-insertion polymorphism in three subethnic groups of Kalmyks] 27 Feb 2009
• Evidence for co-evolution between human microRNAs and Alu-repeats. 9 Feb 2009
• Rare mutations of FGFR2 causing apert syndrome: identification of the first partial gene deletion, and an Alu element insertion from a new subfamily. 30 Jan 2009
• Lineage specific evolutionary events on SFTPB gene: Alu recombination-mediated deletion (ARMD), exonization, and alternative splicing events. 21 Jan 2009
• Polymorphic Alu insertions and their associations with MHC class I alleles and haplotypes in Han and Jinuo populations in Yunnan Province, southwest of China. 30 Dec 2008
• Chromosomal losses are associated with hypomethylation of the gene-control regions in the stomach with a low number of active genes. 22 Dec 2008
• Gene flow and genetic structure in the Galician population (NW Spain) according to Alu insertions. 30 Nov 2008
• Polymorphic insertions in 5 Alu loci within the major histocompatibility complex class I region and their linkage disequilibria with HLA alleles in four distinct populations in mainland China. 29 Nov 2008
• A PCR-based marker to simply identify Saimiri sciureus and S. boliviensis boliviensis. 29 Nov 2008

See a longer list of these articles.

Technical information about 'Alu Elements'

Definition: The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.

Descriptor UI: D020087

Alternative terms: Alu Elements; Alu Element; Element, Alu; Elements, Alu; Alu Family; Alu Families; Families, Alu; Family, Alu; Alu Repetitive Sequences; Alu Repetitive Sequence; Repetitive Sequence, Alu; Repetitive Sequences, Alu; Sequence, Alu Repetitive; Sequences, Alu Repetitive; Alu-Like Repetitive Sequence;

Related Mesh Headings: Mutagenesis, Insertional;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.570.080.708.330.800.800.050; G05.360.080.708.330.800.800.050; G05.360.340.024.425.800.800.050;

History Note: 99; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98