Alzheimer Disease - Complications
Research News and Information

Saturday, November 21, 2009

The clinical course of advanced dementia.

13 Oct 2009 BACKGROUND: Dementia is a leading cause of death in the United States but is underrecognized as a terminal illness. The clinical course of nursing home residents with advanced dementia has not been well described. METHODS: We followed 323 nursing ... Read more...

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

12 Oct 2009 Upon activation by calcineurin, the nuclear factor of activated T-cells (NFAT) translocates to the nucleus and guides the transcription of numerous molecules involved in inflammation and Ca(2+) dysregulation, both of which are prominent features of ... Read more...

[Pain assessment in dementia]

6 Oct 2009 BACKGROUND: Patients with dementia are often unable to describe their pain because of memory deficiency and speech problems. This may lead to under-diagnosing and suboptimal pain treatment. The article summarises a thesis on development and testing ... Read more...

Latest indexed articles for 'Alzheimer Disease - Complications'

These are the very latest articles for this heading:

• The clinical course of advanced dementia. 13 Oct 2009
• Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. 12 Oct 2009
• [Pain assessment in dementia] 6 Oct 2009
• Verbal learning in Alzheimer's disease: cumulative word knowledge gains across learning trials. 30 Aug 2009
• Semantic inhibition impairment in mild cognitive impairment: a distinctive feature of upcoming cognitive decline? 30 Aug 2009
• Akinetopsia in the posterior cortical variant of Alzheimer disease. 30 Aug 2009
• Insulin resistance and Alzheimer's disease. 29 Aug 2009
• Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice. 24 Aug 2009
• Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding. 16 Aug 2009
• 123I-5-IA-85380 SPECT imaging of nicotinic receptors in Alzheimer disease and mild cognitive impairment. 16 Aug 2009
• JAMA patient page. Dementia. 10 Aug 2009
• Oxygen treatment triggers cognitive impairment in Alzheimer's transgenic mice. 3 Aug 2009
• Parallel imaging: is GRAPPA a useful acquisition tool for MR imaging intended for volumetric brain analysis? Aug 2009
• [Oldest-old dementia in a Japanese memory clinic] 30 Jul 2009
• Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil. 30 Jul 2009
• Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease. 29 Jul 2009
• [Usage of drugs with potential adverse effects on cognition in a memory-clinic] 28 Jul 2009
• Amyloid imaging in the prediction of Alzheimer-type dementia in subjects with amnestic MCI. 27 Jul 2009
• INECO Frontal Screening (IFS): a brief, sensitive, and specific tool to assess executive functions in dementia. 26 Jul 2009
• Effect of music therapy on anxiety and depression in patients with Alzheimer's type dementia: randomised, controlled study. 21 Jul 2009

See a longer list of these articles.

Technical information about 'Alzheimer Disease'

Definition: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Descriptor UI: D000544

Alternative terms: Alzheimer Disease; Disease, Alzheimer; Dementia, Senile; Dementias, Senile; Senile Dementia; Senile Dementias; Dementia, Primary Senile Degenerative; Senile Dementia, Alzheimer Type; Alzheimer Type Senile Dementia; Primary Senile Degenerative Dementia; Alzheimer's Disease; Disease, Alzheimer's; Dementia, Alzheimer Type; Alzheimer Type Dementia; Dementia, Presenile; Dementias, Presenile; Presenile Dementia; Presenile Dementias; Alzheimer Disease, Late Onset; Late Onset Alzheimer Disease; Alzheimer's Disease, Focal Onset; Focal Onset Alzheimer's Disease; Acute Confusional Senile Dementia; Senile Dementia, Acute Confusional; Alzheimer Disease, Early Onset; Early Onset Alzheimer Disease; Presenile Alzheimer Dementia; Alzheimer Dementia, Presenile; Dementia, Presenile Alzheimer;

Related Mesh Headings: Amyloid beta-Protein; Amyloid beta-Protein Precursor; Cerebral Amyloid Angiopathy; tau Proteins; Neurofilament Proteins; Aphasia, Primary Progressive; Kluver-Bucy Syndrome;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.380.100; C10.574.945.249; F03.087.400.100;

History Note: 1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999