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Alzheimer Disease - Research News and Information
Wednesday, January 07, 2009
Definition of 'Alzheimer Disease'A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study.
2 Nov 2008 
OBJECTIVE: To investigate longitudinal change in the medical decision-making capacity (MDC) of patients with amnestic mild cognitive impairment (MCI) under different consent standards. METHODS: Eighty-eight healthy older controls and 116 patients ... Read more...
Survival in Alzheimer disease: a multiethnic, population-based study of incident cases.
2 Nov 2008 OBJECTIVE: To describe factors associated with survival in Alzheimer disease (AD) in a multiethnic, population-based longitudinal study. METHODS: AD cases were identified in the Washington Heights Inwood Columbia Aging Project, a longitudinal, ... Read more...
Incidence of early-onset dementias in Cambridgeshire, United Kingdom.
2 Nov 2008 OBJECTIVE: To estimate the incidence of early-onset dementias in a defined area of Cambridgeshire served by Addenbrooke's Hospital. METHODS: The area selected for the study was that covered by the local authority areas of Cambridge City, East ... Read more...
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Latest indexed articles for 'Alzheimer Disease'
These are the very latest articles for this heading:
- Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study. 2 Nov 2008
- Survival in Alzheimer disease: a multiethnic, population-based study of incident cases. 2 Nov 2008
- Incidence of early-onset dementias in Cambridgeshire, United Kingdom. 2 Nov 2008
- The effects of stress and APOE genotype on cognition in older adults.
30 Oct 2008 - Lithium treatment and risk of dementia. 30 Oct 2008
- Education and occupation as proxies for reserve in aMCI converters and AD: FDG-PET evidence. 19 Oct 2008
- Amyloid-beta vaccination for Alzheimer's dementia. 16 Oct 2008
- Amyloid-beta vaccination for Alzheimer's dementia. 16 Oct 2008
- Statistical treatment of withdrawal in trials of anti-dementia drugs. 16 Oct 2008
- High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial. 13 Oct 2008
- B vitamins for prevention of cognitive decline: insufficient evidence to justify treatment. 13 Oct 2008
- Amyloid beta-Cu2+ complexes in both monomeric and fibrillar forms do not generate H2O2 catalytically but quench hydroxyl radicals. 9 Oct 2008
- Diagnosis and treatment of dementia: 4. Approach to management of mild to moderate dementia.
5 Oct 2008 - Subjective cognitive failures and hippocampal volume in elderly with white matter lesions. 5 Oct 2008
- Invited article: the Alzheimer disease-frontotemporal lobar degeneration spectrum. 5 Oct 2008
- The journey. 5 Oct 2008
- Dementia in fragile X-associated tremor/ataxia syndrome (FXTAS): comparison with Alzheimer's disease. 3 Oct 2008
- Association of adiposity status and changes in early to mid-adulthood with incidence of Alzheimer's disease. Oct 2008
- Structural and dynamical studies of Humanin in water and TFE/water mixture: a molecular dynamics simulation. 29 Sep 2008
- Donepezil: potential neuroprotective and disease-modifying effects. 29 Sep 2008
See a longer list of these articles.
Technical information about 'Alzheimer Disease'
Definition: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Descriptor UI: D000544
Alternative terms: Alzheimer Disease; Disease, Alzheimer; Dementia, Senile; Dementias, Senile; Senile Dementia; Senile Dementias; Dementia, Primary Senile Degenerative; Senile Dementia, Alzheimer Type; Alzheimer Type Senile Dementia; Primary Senile Degenerative Dementia; Alzheimer's Disease; Disease, Alzheimer's; Dementia, Alzheimer Type; Alzheimer Type Dementia; Dementia, Presenile; Dementias, Presenile; Presenile Dementia; Presenile Dementias; Alzheimer Disease, Late Onset; Late Onset Alzheimer Disease; Alzheimer's Disease, Focal Onset; Focal Onset Alzheimer's Disease; Acute Confusional Senile Dementia; Senile Dementia, Acute Confusional; Alzheimer Disease, Early Onset; Early Onset Alzheimer Disease; Presenile Alzheimer Dementia; Alzheimer Dementia, Presenile; Dementia, Presenile Alzheimer;
Related Mesh Headings: Amyloid beta-Protein; Amyloid beta-Protein Precursor; Cerebral Amyloid Angiopathy; tau Proteins; Neurofilament Proteins; Aphasia, Primary Progressive; Kluver-Bucy Syndrome;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.140.380.100; C10.574.945.249; F03.087.400.100;
History Note: 1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999