Amino Acid Motifs
Research News and Information

Sunday, November 22, 2009

Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval.

29 Nov 2009 ClC-2 chloride channel is present in the brain and some transporting epithelia where its function is poorly understood. We have now demonstrated that the surface channels are rapidly internalised and approximately the 70% of the surface membrane ... Read more...

Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain.

8 Nov 2009 NKX3.1 is a prostate tumor suppressor belonging to the NK-2 family of homeodomain (HD) transcription factors. NK-2 family members often possess a stretch of 10-15 residues enriched in acidic amino acids, the acidic domain (AD), in the flexible, ... Read more...

Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence.

30 Oct 2009 It has been recently found that muscle fructose 1,6-bisphosphatase (FBPase) is actively transported into cells' nuclei. Results of an analysis in silico of muscle FBPase structure gave rise to a hypothesis that sequence (203)KKKGK(207) is ... Read more...

Latest indexed articles for 'Amino Acid Motifs'

These are the very latest articles for this heading:

• Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. 29 Nov 2009
• Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain. 8 Nov 2009
• Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence. 30 Oct 2009
• Prion protein region 23-32 interacts with tubulin and inhibits microtubule assembly. 30 Oct 2009
• KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. 24 Oct 2009
• The ARH adaptor protein regulates endocytosis of the ROMK potassium secretory channel in mouse kidney. 17 Oct 2009
• Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. 16 Oct 2009
• Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations. 12 Oct 2009
• Residues K128, 132, and 134 in the thyroid hormone receptor-alpha are essential for receptor acetylation and activity. 7 Oct 2009
• Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors. 3 Oct 2009
• Automated scaffold selection for enzyme design. 29 Sep 2009
• The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. 28 Sep 2009
• Permutation of the active site of putative RNA-dependent RNA polymerase in a newly identified species of plant alpha-like virus. 27 Sep 2009
• Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant. 23 Sep 2009
• Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. 23 Sep 2009
• Binding to PCNA in Euryarchaeal DNA Replication requires two PIP motifs for DNA polymerase D and one PIP motif for DNA polymerase B. 21 Sep 2009
• The glutamate switch is present in all seven clades of AAA+ protein. 20 Sep 2009
• Solution structure of Psb27 from cyanobacterial photosystem II. 20 Sep 2009
• Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs. 16 Sep 2009
• Quadruple 9-mer-based protein binding microarray with DsRed fusion protein. 16 Sep 2009

See a longer list of these articles.

Technical information about 'Amino Acid Motifs'

Definition: Commonly observed structural components of proteins formed by simple combinations of adjacent secondary structures. A commonly observed structure may be composed of a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.

Descriptor UI: D020816

Alternative terms: Amino Acid Motifs; Amino Acid Motif; Motif, Amino Acid; Motifs, Amino Acid; Protein Motifs; Motif, Protein; Motifs, Protein; Protein Motif; Protein Structure, Supersecondary; Protein Structures, Supersecondary; Supersecondary Protein Structures; Supersecondary Protein Structure;

Related Mesh Headings: Consensus Sequence; Conserved Sequence;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.570.060.040; G02.111.570.790.709.600.040;

History Note: 2000

Technical Notes: IM general; coord NIM with specific protein (IM); PROTEIN DOMAINS see PROTEIN STRUCTURE, TERTIARY is available; if the amino acid motif is a representative of conserved sequence then also index CONSENSUS SEQUENCE; DF: AA MOTIFS