Amnesia - Enzymology
Research News and Information

Monday, November 23, 2009

Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice.

25 May 2009 We examined anti-amnesic activity of the methanolic extract of Cornus officinalis fruits (COT) and a major constituent, loganin using scopolamine-induced (1 mg/kg body weight, s.c.) amnesic mice with both passive avoidance and the Morris water maze ... Read more...

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease.

30 Jul 2008 OBJECTIVE: To evaluate the safety, tolerability, and amyloid beta (Abeta) response to the gamma-secretase inhibitor LY450139 in Alzheimer disease. DESIGN: Multicenter, randomized, double-blind, dose-escalation, placebo-controlled trial. SETTING: ... Read more...

Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment.

4 Mar 2008 Mild cognitive impairment (MCI) is generally referred to the transitional zone between normal cognitive aging and early dementia or clinically probable Alzheimer's disease (AD). Most individuals with amnestic MCI eventually develop AD, which ... Read more...

Latest indexed articles for 'Amnesia - Enzymology'

These are the very latest articles for this heading:

• Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice. 25 May 2009
• Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease. 30 Jul 2008
• Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment. 4 Mar 2008
• Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. 15 Aug 2007
• Inhibition of the MAPK/ERK cascade: a potential transcription-dependent mechanism for the amnesic effect of anesthetic propofol. 27 Feb 2007
• Influence of nitric oxide on morphine-induced amnesia and interactions with dopaminergic receptor agents. 19 Apr 2006
• Daidzein activates choline acetyltransferase from MC-IXC cells and improves drug-induced amnesia. 30 Dec 2005
• Status of the "protein kinase CK2-HMG14" system in age-related amnesia in rats. 29 Sep 2003
• Effects of nefiracetam, DM-9384 on amnesia and decrease in choline acetyltransferase activity induced by cycloheximide. 30 Dec 1991
• [Cytology, lactate dehydrogenase, and creatine kinase in CSF in mild head injuries (author's transl)] 20 Aug 1978
• When does inhibition of brain acetylcholinesterase cause amnesia in rats? 23 Feb 1977
• Biochemical actions of sympathomimetic drugs which overcome cycloheximide-induced amnesia. 30 Oct 1976
• Recovery from amnesia induced by pre-test injections of monoamine oxidase inhibitors. 29 Apr 1974

See a longer list of these articles.

Technical information about 'Amnesia'

Definition: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Descriptor UI: D000647

Alternative terms: Amnesia; Amnesias; Amnesia-Memory Loss; Amnesia Memory Loss; Amnesia-Memory Losses; Amnesia, Global; Amnesias, Global; Global Amnesia; Global Amnesias; Amnestic State; Amnestic States; State, Amnestic; States, Amnestic; Amnesia, Tactile; Amnesias, Tactile; Tactile Amnesia; Tactile Amnesias; Amnesia, Temporary; Amnesias, Temporary; Temporary Amnesia; Temporary Amnesias; Amnesia, Dissociative; Amnesias, Dissociative; Dissociative Amnesia; Dissociative Amnesias; Amnesia, Hysterical; Amnesias, Hysterical; Hysterical Amnesia; Hysterical Amnesias;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: C10.597.606.525.100; C23.888.592.604.529.100; F01.700.625.100; F03.087.200;