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Amyotrophic Lateral Sclerosis - Complications
Research News and Information
Definition of 'Amyotrophic Lateral Sclerosis'A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) |
Monday, November 23, 2009
Prevalence of fatigue and depression in ALS patients and change over time.
29 Sep 2009 
BACKGROUND: Amyotrophic lateral sclerosis (ALS) patients report both fatigue and depression. It is not clear how frequently each occurs, to what extent they occur together, how each relates to ALS disease status, or their stability over time. ... Read more...
Fully intact contact heat evoked potentials in patients with amyotrophic lateral sclerosis.
30 May 2009 Amyotrophic lateral sclerosis (ALS) is typically considered to be a disease of motor, not sensory, neurons. However, reports exist of sensory system involvement in ALS. In this study we aimed to study the characteristic of contact heat-evoked ... Read more...
Defining survival as an outcome measure in amyotrophic lateral sclerosis.
30 May 2009 OBJECTIVES: To examine how respiratory interventions affect survival as an outcome measure and to define survival rate for trials in amyotrophic lateral sclerosis. DESIGN AND SETTING: We reviewed the data of 3 phase 3 clinical trials and examined ... Read more...
Latest indexed articles for 'Amyotrophic Lateral Sclerosis - Complications'
These are the very latest articles for this heading:
- Prevalence of fatigue and depression in ALS patients and change over time. 29 Sep 2009
- REM sleep behavior disorder in patients with DJ-1 mutations and parkinsonism-dementia-ALS complex.
28 Jul 2009 - Fully intact contact heat evoked potentials in patients with amyotrophic lateral sclerosis. 30 May 2009
- Defining survival as an outcome measure in amyotrophic lateral sclerosis. 30 May 2009
- Percutaneous nocturnal oximetry in amyotrophic lateral sclerosis: periodic desaturation. 30 May 2009
- Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. 30 May 2009
- Accumulation of TDP-43 and alpha-actin in an amyotrophic lateral sclerosis patient with the K17I ANG mutation. 14 May 2009
- Pathological gambling amongst Parkinson's disease and ALS patients in an online community (PatientsLikeMe.com). 13 May 2009
- Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter. 29 Apr 2009
- Agraphia in intellectually normal Japanese patients with ALS: omission of kana letters. 16 Apr 2009
- Hyperexcitability, persistent Na+ conductances and neurodegeneration in amyotrophic lateral sclerosis. 6 Apr 2009
- Predicting respiratory insufficiency in amyotrophic lateral sclerosis: the role of phrenic nerve studies. 30 Mar 2009
- Penn State screen exam for the detection of frontal and temporal dysfunction syndromes: application to ALS. 30 Mar 2009
- Cognitive deficits in amyotrophic lateral sclerosis evaluated by event-related potentials. 30 Mar 2009
- Identification of cognitive deficits in amyotrophic lateral sclerosis. 12 Mar 2009
- Early treatment with noninvasive positive pressure ventilation prolongs survival in Amyotrophic Lateral Sclerosis patients with nocturnal respiratory insufficiency.
8 Mar 2009 - Re: Dyslipidemia is a protective factor in amyotrophic lateral sclerosis. 8 Mar 2009
- Combined spinal-epidural block in a patient with amyotrophic lateral sclerosis: case report. 27 Feb 2009
- SOD1 and cognitive dysfunction in familial amyotrophic lateral sclerosis. 27 Feb 2009
- Can't we get this over with?: an approach to assessing the patient who requests hastened death. 27 Feb 2009
See a longer list of these articles.
Technical information about 'Amyotrophic Lateral Sclerosis'
Definition: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
Descriptor UI: D000690
Alternative terms: Amyotrophic Lateral Sclerosis; Lateral Scleroses, Amyotrophic; Sclerosis, Amyotrophic Lateral; ALS (Amyotrophic Lateral Sclerosis); Lou Gehrig Disease; Gehrig's Disease; Gehrig Disease; Gehrigs Disease; Lou Gehrig's Disease; Lou Gehrigs Disease; Motor Neuron Disease, Amyotrophic Lateral Sclerosis; Amyotrophic Lateral Sclerosis, Guam Form; Guam Form of Amyotrophic Lateral Sclerosis; Amyotrophic Lateral Sclerosis With Dementia; Dementia With Amyotrophic Lateral Sclerosis;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.854.139; C10.574.562.250; C10.668.460.250;