Anacardic Acids
Research News and Information

Sunday, November 22, 2009

Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites.

8 Jul 2009 Endothelin-1 (ET-1) is a potent vasoconstrictor and co-mitogen for vascular smooth muscle and is implicated in pulmonary vascular remodeling and the development of pulmonary arterial hypertension. Vascular smooth muscle is an important source of ... Read more...

Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate.

25 Feb 2009 Protein modification by small ubiquitin-related modifier proteins (SUMOs) controls diverse cellular functions. Dysregulation of SUMOylation or deSUMOylation processes has been implicated in the development of cancer and neurodegenerative diseases. ... Read more...

Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity.

3 Feb 2009 Several benzamide derivatives were synthesized from anacardic acid (1a) which was the product of hydrogenation of the naturally occurring anacardic acid mixture (1a-d), a major constituent of cashew nut shell liquid. Anacardic acid (1a) was first ... Read more...

Latest indexed articles for 'Anacardic Acids'

These are the very latest articles for this heading:

• Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites. 8 Jul 2009
• Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. 25 Feb 2009
• Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity. 3 Feb 2009
• Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. 22 Dec 2008
• Bioassay-guided isolation of antiplasmodial anacardic acids derivatives from the whole plants of Viola websteri Hemsl. 29 Sep 2008
• Isolation of anacardic acid from natural cashew nut shell liquid (CNSL) using supercritical carbon dioxide. 22 Sep 2008
• Effects of immature cashew nut-shell liquid (Anacardium occidentale) against oxidative damage in Saccharomyces cerevisiae and inhibition of acetylcholinesterase activity. 7 Sep 2008
• Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities. 30 Aug 2008
• Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. 27 Aug 2008
• Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. 13 Jul 2008
• Enzymatic polymerization of natural anacardic acid and antibiofouling effects of polyanacardic acid coatings. 29 Jun 2008
• Evaluation of lipoxygenase inhibitory activity of anacardic acids. 29 Jun 2008
• Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development. 14 May 2008
• Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. 16 Mar 2008
• Difluoromethylornithine stimulates early cardiac commitment of mesenchymal stem cells in a model of mixed culture with cardiomyocytes. 28 Feb 2008
• Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. 22 Jan 2008
• Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid. 8 Oct 2007
• Design and evaluation of anacardic acid derivatives as anticavity agents. 12 Sep 2007
• Anacardic acids and ferric ion chelation. 30 Aug 2007
• Characterization of novel inhibitors of histone acetyltransferases. 30 Aug 2007

See a longer list of these articles.

Technical information about 'Anacardic Acids'

Definition: A group of 6-alkyl SALICYLIC ACIDS that are found in ANACARDIUM and known for causing CONTACT DERMATITIS.

Registry Number: 0

Descriptor UI: D048729

Alternative terms: Anacardic Acids; Acids, Anacardic; Salicylic Acids, 6-Alkyl; Salicylic Acids, 6 Alkyl;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.241.223.100.380.800.062; D02.241.511.390.700.062; D02.755.410.700.062;

History Note: 2005