Analgesics, Non-Narcotic - Adverse effects
Research News and Information

Sunday, November 22, 2009

Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption.

5 Aug 2009 BACKGROUND: Panadol Osteo (GlaxoSmithKline) is a modified-release paracetamol formulation marketed in Australia and New Zealand, comprising 33% immediate and 66% sustained-release fractions. In overdose, absorption may be delayed and the paracetamol ... Read more...

Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.

6 Jul 2009 BACKGROUND: Oxycodone is a strong opioid agonist used to treat severe pain. It is commonly combined with milder analgesics such as paracetamol. This review updates a previous review that concluded, based on limited data, that all doses of oxycodone ... Read more...

Single dose oral ibuprofen for acute postoperative pain in adults.

6 Jul 2009 BACKGROUND: This review updates a 1999 Cochrane review showing that ibuprofen at various doses was effective in postoperative pain in single dose studies designed to demonstrate analgesic efficacy. New studies have since been published. Ibuprofen is ... Read more...

Latest indexed articles for 'Analgesics, Non-Narcotic - Adverse effects'

These are the very latest articles for this heading:

• FDA's acetaminophen meeting sparks confusion, uncertainty. 13 Aug 2009
• Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption. 5 Aug 2009
• Unnecessary medicines? 30 Jul 2009
• Foreword. Drug allergy and primum non-nocere. 30 Jul 2009
• FDA focuses on drugs and liver damage: labeling and other changes for acetaminophen. 20 Jul 2009
• More on fixed drug eruptions. 19 Jul 2009
• Acetaminophen safety - deja vu. 11 Jul 2009
• Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults. 6 Jul 2009
• Single dose oral ibuprofen for acute postoperative pain in adults. 6 Jul 2009
• Does 1 or 2 g paracetamol added to ketoprofen enhance analgesia in adult tonsillectomy patients? 28 Jun 2009
• Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. 16 Jun 2009
• [Concomitant use of warfarin, analgesics and anti-inflammatory agents] 9 Jun 2009
• Successful management of necrotizing pancreatitis by percutaneous necrosectomy after orthotopic liver transplant for paracetamol induced acute liver failure: a case report. 30 May 2009
• Aspirin or paracetamol - what's good for you? 30 May 2009
• A randomized, double blind, placebo-controlled study of MAP0004 in adult patients with migraine. 30 May 2009
• A randomized, placebo-controlled clinical trial of chiropractic and medical prophylactic treatment of adults with tension-type headache: results from a stopped trial. 30 May 2009
• The utilization of liver transplantation in the management of acute liver failure: comparison between acetaminophen and non-acetaminophen etiologies. 30 May 2009
• Thinking through acetaminophen hepatotoxicity and liver transplantation: choosing worthy recipients. 30 May 2009
• Levomepromazine-induced lupus? 30 May 2009
• Amantadine-associated corneal edema. 30 May 2009

See a longer list of these articles.

Technical information about 'Analgesics, Non-Narcotic'

Definition: Drugs that have principally analgesic, antipyretic, and anti-inflammatory actions. They do not bind to opioid receptors and are not classified under the Controlled Substances Act. (From Drug Evaluations Annual, 1992, p109)

Registry Number: 0

Descriptor UI: D018712

Alternative terms: Analgesics, Non-Narcotic; Analgesics, Non Narcotic; Non-Narcotic Analgesics; Analgesics, Nonopioid; Nonopioid Analgesics; Analgesics, Nonnarcotic; Nonnarcotic Analgesics; Antipyretics;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.850.014.040; D27.505.954.427.040.100;

Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANTIPYRETICS 1978-94; use ANALGESICS 1966-77

History Note: 95; ANTIPYRETICS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1990-94; was see ANALGESICS, ANTI-INFAMMATORY 1978-89; was see ANALGESICS AND ANTIPYRETICS 1975-77; was see under ANALGESICS AND ANTIPYRETICS 1963-74

Technical Notes: GEN or unspecified: prefer specifics