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Analgesics, Non-Narcotic - Chemical synthesis
Research News and Information
Definition of 'Analgesics, Non-Narcotic'Drugs that have principally analgesic, antipyretic, and anti-inflammatory actions. They do not bind to opioid receptors and are not classified under the Controlled Substances Act. (From Drug Evaluations Annual, 1992, p109) Common names: Analgesics, Non-Narcotic; Analgesics, Non Narcotic; Non-Narcotic Analgesics; Analgesics, Nonopioid; Nonopioid Analgesics; Analgesics, Nonnarcotic; Nonnarcotic Analgesics; Antipyretics |
Wednesday, March 10, 2010
24 Sep 2009 
Andrographolide (1) and 14-deoxy-11,12-didehydroandrographolide (2) are active constituents of Andrographis paniculata (Burm. f.), family Acanthaceae. A. paniculata extracts are reported to have antiviral, antipyretic, immunostimulant and anticancer ... Read more...
11 Jun 2009 8-Acetyl-7-hydroxy-4-phenyl-2H-benzopyran-2-one as starting material a number of 8-substituted derivatives (i.e., hydrazones 2a,b, imine 2c, chalcones 3, pyrazoles 4, 3-cyano-2-oxo-dihydropyridines 5, and/or 3-cyano-2-imino-dihydropyridines 6) were ... Read more...
29 Apr 2009 Condensation of 2-acetyltetralin with ethylcyanoacetate and/or malononitrile and some aldehydes in the presence of excess of ammonium acetate afforded the respective hydroxycyanopyridines or aminocyanopyridines 1a-f and 2a-f. Treatment of ... Read more...
Latest indexed articles for 'Analgesics, Non-Narcotic - Chemical synthesis'
These are the very latest articles for this heading:
- Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals. 24 Sep 2009
- Synthesis, biological evaluation and docking studies of novel benzopyranone congeners for their expected activity as anti-inflammatory, analgesic and antipyretic agents. 11 Jun 2009
- Synthesis of novel tetrahydronaphthalen-2-yl heterocycles for analgesic, anti-inflammatory and antipyretic evaluation. 29 Apr 2009
- Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety. 12 Apr 2009
- Studies on synthesis and pharmacological activities of 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles and their dihydro analogues. 30 Mar 2009
- Synthesis and analgesic and anti-inflammatory activity of 6-phenyl/(4-methylphenyl)-3(2H)-pyridazinon-2-propionamide derivatives. 30 Dec 2008
- Design, synthesis and pharmacological evaluation of a series of 5-carbethoxy-4-chloro-6-(substituted amino)pyrimidines as potential analgesic and anti-flammatory agents with very low ulcerogenic potential. 30 Dec 2008
- Synthesis and study on analgesic effects of 1-[1-(4-methylphenyl) (cyclohexyl)] 4-piperidinol and 1-[1-(4-methoxyphenyl) (cyclohexyl)] 4-piperidinol as two new phencyclidine derivatives. 30 Dec 2008
- Synthesis and pharmacological evaluation of N-(dimethylamino)ethyl derivatives of benzo- and pyridopyridazinones. 30 Dec 2008
- Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. 4 May 2008
- Isotopic ratios to detect infringements of patents or proprietary processes of pharmaceuticals: two case studies. 27 Apr 2008
- Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies. 5 Apr 2008
- Selenium-containing heterocycles: synthesis and pharmacological activities of some new 4-methylquinoline-2(1H) selenone derivatives. 30 Mar 2008
- Synthesis and evaluation of antiinflammatory and analgesic activities of a novel series of coumarin Mannich bases. 30 Dec 2007
- Synthesis, analgesic and anti inflammatory activities of some new fenamate analogues. 30 Dec 2007
- Synthesis and evaluation of analgesic, anti-inflammatory and antioxidant activities of new 6-acyl-3-alkyl-5-methyl-2(3H)-benzoxazolones. 30 Dec 2007
- Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. 15 Oct 2007
- Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activity. 19 Sep 2007
- Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity. 9 Sep 2007
- Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity. 30 Mar 2007
See a longer list of these articles.
Technical information about 'Analgesics, Non-Narcotic'
Definition: Drugs that have principally analgesic, antipyretic, and anti-inflammatory actions. They do not bind to opioid receptors and are not classified under the Controlled Substances Act. (From Drug Evaluations Annual, 1992, p109)
Registry Number: 0
Descriptor UI: D018712
Alternative terms: Analgesics, Non-Narcotic; Analgesics, Non Narcotic; Non-Narcotic Analgesics; Analgesics, Nonopioid; Nonopioid Analgesics; Analgesics, Nonnarcotic; Nonnarcotic Analgesics; Antipyretics;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D27.505.696.663.850.014.040; D27.505.954.427.040.100;
Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANTIPYRETICS 1978-94; use ANALGESICS 1966-77
History Note: 95; ANTIPYRETICS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1990-94; was see ANALGESICS, ANTI-INFAMMATORY 1978-89; was see ANALGESICS AND ANTIPYRETICS 1975-77; was see under ANALGESICS AND ANTIPYRETICS 1963-74
Technical Notes: GEN or unspecified: prefer specifics