Analgesics, Opioid - Metabolism
Research News and Information

Sunday, November 22, 2009

Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis.

30 Oct 2009 Preclinical investigations utilizing murine experimental auto-immune encephalomyelitis (EAE), as well as clinical observations in patients with multiple sclerosis (MS), may suggest alteration of endogenous opioid systems in MS. In this study we used ... Read more...

The potency of different serotonergic agonists in counteracting opioid evoked cardiorespiratory disturbances.

10 Sep 2009 Serotonin receptor (5-HTR) agonists that target 5-HT(4(a))R and 5-HT(1A)R can reverse mu-opioid receptor (mu-OR)-evoked respiratory depression. Here, we have tested whether such rescuing by serotonin agonists also applies to the cardiovascular ... Read more...

Evidence for opioid-induced release of glutamate in guinea pig longitudinal muscle-myenteric plexus strip.

30 Jun 2009 By the use of longitudinal muscle-myenteric plexus (LMMP) strips of the guinea pig ileum it should be investigated whether opioids can contribute to an excitatory component of the intestinal smooth muscle contractions. LMMP preparations were set up ... Read more...

Latest indexed articles for 'Analgesics, Opioid - Metabolism'

These are the very latest articles for this heading:

• Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis. 30 Oct 2009
• The potency of different serotonergic agonists in counteracting opioid evoked cardiorespiratory disturbances. 10 Sep 2009
• Codeine, ultrarapid-metabolism genotype, and postoperative death. 18 Aug 2009
• Evidence for opioid-induced release of glutamate in guinea pig longitudinal muscle-myenteric plexus strip. 30 Jun 2009
• Update on abuse-resistant and abuse-deterrent approaches to opioid formulations. 29 Jun 2009
• Universal precautions revisited: managing the inherited pain patient. 29 Jun 2009
• Codeine and morphine pathway. 29 Jun 2009
• Opioid metabolism. 29 Jun 2009
• Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2. 17 Jun 2009
• The in vivo response of novel buprenorphine metabolites, M1 and M3, to antiretroviral inducers and inhibitors of buprenorphine metabolism. 2 Jun 2009
• Simultaneous quantification of methadone, cocaine, opiates, and metabolites in human placenta by liquid chromatography-mass spectrometry. 30 May 2009
• Can heterogeneity of chronic sickle-cell disease pain be explained by genomics? A literature review. 30 May 2009
• Opioid and progesterone signaling is obligatory for early human embryogenesis. 30 May 2009
• Pleiotropic effects of morphine-6beta-glucuronide. 30 May 2009
• Effect of buspirone on thermal sensory and pain thresholds in human volunteers. 27 May 2009
• Neurochemical phenotypes of endomorphin-2-containing neurons in vagal nodose neurons of the adult rat. 18 May 2009
• Which cue to "want?" Central amygdala opioid activation enhances and focuses incentive salience on a prepotent reward cue. 18 May 2009
• Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone. 18 May 2009
• Enatiomeric determination of tramadol and O-desmethyltramadol in human urine by gas chromatography-mass spectrometry. May 2009
• Opioids and the skin--where do we stand? 29 Apr 2009

See a longer list of these articles.

Technical information about 'Analgesics, Opioid'

Definition: Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.

Registry Number: 0

Descriptor UI: D000701

Alternative terms: Analgesics, Opioid; Opioid Analgesics; Opioids;

Related Mesh Headings: Opioid-Related Disorders;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.850.014.520; D27.505.954.427.040.325; D27.505.954.427.210.049;

Online Note: use ANALGESICS, OPIOID to search ANALGESICS, ADDICTIVE 1975-94

History Note: 95; was ANALGESICS, ADDICTIVE 1975-94