 |
Androgen-Insensitivity Syndrome - Research News and Information
Wednesday, January 07, 2009
Definition of 'Androgen-Insensitivity Syndrome'A familial form of PSEUDOHERMAPHRODITISM transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY. |
Complete androgen insensitivity: the role of the surgeon.
18 Aug 2008 
PURPOSE: This is a retrospective series of the surgical management of complete androgen insensitivity at a single institution. MATERIALS AND METHODS: The records of 16 patients 4 to 63 years old with complete androgen insensitivity were extracted ... Read more...
14 Aug 2008 PURPOSE: Diagnosis and management of the complete androgen insensitivity syndrome have dramatically changed in the last few decades, with earlier diagnosis and the development of molecular biology. Some phenotypic features such as development of ... Read more...
Gynecomastia in prepubertal and pubertal men.
30 Jul 2008 PURPOSE OF REVIEW: Gynecomastia is often benign, but it can be the sign of serious endocrine disease and the source of significant embarrassment and psychological stress. Understanding its pathogenesis is crucial to distinguish a normal ... Read more...
Learn Faster Today Improve your study skills
Latest indexed articles for 'Androgen-Insensitivity Syndrome'
These are the very latest articles for this heading:
- Complete androgen insensitivity: the role of the surgeon. 18 Aug 2008
- Long-term followup and comparison between genotype and phenotype in 29 cases of complete androgen insensitivity syndrome. 14 Aug 2008
- Gynecomastia in prepubertal and pubertal men. 30 Jul 2008
- Androgen insensitivity syndrome: clinical features and molecular defects.
29 Jun 2008 - Complete Androgen Insensitivity Syndrome. 29 Jun 2008
- Androgen receptors are required for full masculinization of nitric oxide synthase system in rat limbic-hypothalamic region. 4 Jun 2008
- [Complete androgen insensitivity syndrome: diagnosis and clinical characteristics] 30 May 2008
- Robotic sigmoid vaginoplasty: a novel technique. 25 May 2008
- Sexually dimorphic gastrin releasing peptide system in the spinal cord controls male reproductive functions. 16 May 2008
- Comparison of bone mineral density and body proportions between women with complete androgen insensitivity syndrome and women with gonadal dysgenesis. 5 May 2008
- [Complete androgen insensitivity syndrome: a novel mutation in a Tunisian family] 4 May 2008
- Familial complete androgen insensitivity syndrome (Morris syndrome or testicular feminization syndrome) in 2 sisters.
28 Feb 2008 - [Androgen insensitivity syndrome] 26 Feb 2008
- Novel missense mutation in the P-box of androgen receptor in a patient with androgen insensitivity syndrome. 11 Feb 2008
- Laparoscopy and intersex: report of 5 cases of male pseudohermaphroditism. 30 Jan 2008
- Gene symbol: AR. Disease: Androgen insensitivity syndrome. 30 Jan 2008
- Gene symbol: AR. Disease: Androgen insensitivity syndrome. 30 Jan 2008
- Cancer of the urinary bladder neovagina in a patient with Morris' syndrome. 20 Jan 2008
- Detection of Y-chromosome in gonadal tumours using fluorescence in situ hybridization: diagnostic value in intersex conditions including older patients with clinically unsuspected androgen insensitivity syndrome. 30 Dec 2007
- Novel mutation in the ligand-binding domain of the androgen receptor gene (l790p) associated with complete androgen insensitivity syndrome. 18 Dec 2007
See a longer list of these articles.
Technical information about 'Androgen-Insensitivity Syndrome'
Definition: A familial form of PSEUDOHERMAPHRODITISM transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY.
Descriptor UI: D013734
Alternative terms: Androgen-Insensitivity Syndrome; Androgen Insensitivity Syndrome; Testicular Feminization; Androgen-Insensitivity Syndrome, Complete; Androgen Insensitivity Syndrome, Complete; Reifenstein Syndrome; Androgen-Insensitivity Syndrome, Partial; Androgen Insensitivity Syndrome, Partial; Androgen-Insensitivity Syndromes, Partial; Reifenstein's Syndrome; Reifensteins Syndrome;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; virology;
Tree Number: C12.706.842.316.627.109; C13.351.875.842.316.627.109; C16.131.939.842.316.627.109; C16.320.322.061; C19.391.775.316.627.500;
History Note: 2002(1968)
Technical Notes: check the tag MALE