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Androgens - Deficiency
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Definition of 'Androgens'

Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Common names: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic

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Sunday, November 22, 2009

Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction.

13 Sep 2009 Obesity is associated with a high prevalence of erectile dysfunction; however, the pathophysiological link between obesity and erectile dysfunction remains poorly understood. In this minireview, we have attempted to evaluate the existing literature ... Read more...


A luminal epithelial stem cell that is a cell of origin for prostate cancer.

7 Sep 2009 In epithelial tissues, the lineage relationship between normal progenitor cells and cell type(s) of origin for cancer has been poorly understood. Here we show that a known regulator of prostate epithelial differentiation, the homeobox gene Nkx3-1, ... Read more...


[Biochemical markers of bone turnover. New aspect. Effects of androgen and estrogen on biochemical markers of bone turnover]

30 Jul 2009 Both androgen and estrogen play important roles in bone metabolism. As estrogen has a potent inhibitory effect on bone resorption, bone turnover increases in postmenopausal osteoprosis caused by estrogen deficiency. Treatment with selective estrogen ... Read more...

 

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Technical information about 'Androgens'

Definition: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Registry Number: 0

Descriptor UI: D000728

Alternative terms: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic;

Related Mesh Headings: Androgen Antagonists; Receptors, Androgen;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.399.472.161;

History Note: 1963

Technical Notes: /defic: consider also HYPOGONADISM & other gonadal disord in Cat C19

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