Androgens - Metabolism
Research News and Information

Sunday, November 22, 2009

Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries.

13 Oct 2009 BACKGROUND: The development and maintenance of the prostate is dependent on androgens and the androgen receptor. The androgen pathway continues to be important in prostate cancer. Here, we evaluated the transcriptome of prostate cancer cells in ... Read more...

Fingers as a marker of prenatal androgen exposure.

7 Oct 2009 Interest in biological substrates of sex-related variations in psychological and physiological characteristics has led to a search for biomarkers of prenatal hormone exposure that can be measured postnatally. There has been particular interest in ... Read more...

Pharmacologic treatment of male breast cancer.

29 Sep 2009 Male breast cancer is an uncommon condition. It often occurs in settings in which there is an imbalance between androgens and oestrogens. Genetics plays an important role, as many cases are associated with mutations in BRCA2 or other genes. Male ... Read more...

Latest indexed articles for 'Androgens - Metabolism'

These are the very latest articles for this heading:

• Key targets of hormone treatment of prostate cancer. Part I: the androgen receptor and steroidogenic pathways. 30 Oct 2009
• Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries. 13 Oct 2009
• Fingers as a marker of prenatal androgen exposure. 7 Oct 2009
• Pharmacologic treatment of male breast cancer. 29 Sep 2009
• Cell cycle regulator cdk2ap1 inhibits prostate cancer cell growth and modifies androgen-responsive pathway function. 29 Sep 2009
• A luminal epithelial stem cell that is a cell of origin for prostate cancer. 7 Sep 2009
• Recent advances in the development of selective androgen receptor modulators. 30 Aug 2009
• The hormonal control of testicular descent. 30 Aug 2009
• Estrogenic and androgenic activity of PCBs, their chlorinated metabolites and other endocrine disruptors estimated with two in vitro yeast assays. 26 Aug 2009
• Yin Yang 1 regulates the transcriptional activity of androgen receptor. 8 Aug 2009
• Initial investigation of amenorrhoea. 2 Aug 2009
• Assignment of the sex of rearing in the neonate with a disorder of sex development. 30 Jul 2009
• Pharmacological options for treatment of hyperandrogenic disorders. 30 Jul 2009
• Detection of prostate specific transcripts in the peripheral blood during brachytherapy predicts postoperative PSA kinetics. 30 Jul 2009
• Ubiquitous mitochondrial creatine kinase is overexpressed in the conditioned medium and the extract of LNCaP lineaged androgen independent cell lines and facilitates prostate cancer progression. 30 Jul 2009
• Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. 21 Jul 2009
• Primary research on Chinese medicine treatment of androgen-independent prostate cancer. 30 Jun 2009
• Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome. 28 Jun 2009
• Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways. 22 Jun 2009
• Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. 20 Jun 2009

See a longer list of these articles.

Technical information about 'Androgens'

Definition: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Registry Number: 0

Descriptor UI: D000728

Alternative terms: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic;

Related Mesh Headings: Androgen Antagonists; Receptors, Androgen;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.399.472.161;

History Note: 1963

Technical Notes: /defic: consider also HYPOGONADISM & other gonadal disord in Cat C19