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Androgens - Therapeutic use
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Definition of 'Androgens'

Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Common names: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic

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Sunday, November 22, 2009

The benefit of ATG in immunosuppressive therapy of children with moderate aplastic anemia.

29 Jun 2009 BACKGROUND: Previous studies specifically focused on the immunosuppressive therapy (IST) of children with moderate aplastic anemia (MAA) are rare. The aim of this study was to evaluate the advantage of using antithymocyte globulin (ATG) in the IST ... Read more...


Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.

24 Jun 2009 Androgens have been used in the treatment of bone marrow failure syndromes without a clear understanding of their mechanism of action. Blood counts of patients with dyskeratosis congenita or aplastic anemia with mutations in telomerase genes can ... Read more...


Effects of testosterone replacement in middle-aged men with dysthymia: a randomized, placebo-controlled clinical trial.

30 May 2009 Mid-life onset male dysthymic disorder (DD) seems to be a distinct clinical condition with limited therapeutic options. Testosterone replacement is mood-enhancing and has been proposed as an antidepressant therapy, though this strategy has received ... Read more...

 

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Technical information about 'Androgens'

Definition: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Registry Number: 0

Descriptor UI: D000728

Alternative terms: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic;

Related Mesh Headings: Androgen Antagonists; Receptors, Androgen;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.399.472.161;

History Note: 1963

Technical Notes: /defic: consider also HYPOGONADISM & other gonadal disord in Cat C19

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