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Androgens
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Definition of 'Androgens'

Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Common names: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic

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Saturday, November 21, 2009

Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries.

13 Oct 2009 BACKGROUND: The development and maintenance of the prostate is dependent on androgens and the androgen receptor. The androgen pathway continues to be important in prostate cancer. Here, we evaluated the transcriptome of prostate cancer cells in ... Read more...


Fingers as a marker of prenatal androgen exposure.

7 Oct 2009 Interest in biological substrates of sex-related variations in psychological and physiological characteristics has led to a search for biomarkers of prenatal hormone exposure that can be measured postnatally. There has been particular interest in ... Read more...


Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms.

5 Oct 2009 Anabolic androgenic steroids (AAS) can promote detrimental effects on social behaviors for which GABA type A (GABA(A)) receptor-mediated circuits in the forebrain play a critical role. While all AAS bind to androgen receptors (AR), they may also be ... Read more...

 

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Technical information about 'Androgens'

Definition: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.

Registry Number: 0

Descriptor UI: D000728

Alternative terms: Androgens; Androgenic Agents; Agents, Androgenic; Androgenic Compounds; Compounds, Androgenic;

Related Mesh Headings: Androgen Antagonists; Receptors, Androgen;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.399.472.161;

History Note: 1963

Technical Notes: /defic: consider also HYPOGONADISM & other gonadal disord in Cat C19

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