Anesthetics, General - Research News and Information

Wednesday, January 07, 2009

The howling cortex: seizures and general anesthetic drugs.

30 Oct 2008 The true incidence of seizures caused by general anesthetic drugs is unknown. Abnormal movements are common during induction of anesthesia, but they may not be indicative of true seizures. Conversely, epileptiform electrocortical activity is ... Read more...

Validation of the index of consciousness during sevoflurane and remifentanil anaesthesia: a comparison with the bispectral index and the cerebral state index.

21 Aug 2008 BACKGROUND: The purpose of this study was to validate a new level of consciousness monitor derived from the EEG, called the index of consciousness (IoC), by comparing it with the bispectral index (BIS) and the cerebral state index (CSI) during ... Read more...

General anesthetics sensitize the capsaicin receptor transient receptor potential V1.

6 Aug 2008 General anesthetics (GAs) are central nervous system depressants that render patients unresponsive to external stimuli. In contrast, many of these agents are also known to stimulate peripheral sensory nerves, raising the possibility that they may ... Read more...

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Latest indexed articles for 'Anesthetics, General'

These are the very latest articles for this heading:

• Awareness and anaesthesia. 30 Oct 2008
• The howling cortex: seizures and general anesthetic drugs. 30 Oct 2008
• Anaesthetists be'ware ... and alarmed. 29 Sep 2008
• Validation of the index of consciousness during sevoflurane and remifentanil anaesthesia: a comparison with the bispectral index and the cerebral state index. 21 Aug 2008
• General anesthetics sensitize the capsaicin receptor transient receptor potential V1. 6 Aug 2008
• General anesthetics have additive actions on three ligand gated ion channels. 30 Jul 2008
• Uneventful anaesthesia does not exclude malignant hyperthermia. 30 Jul 2008
• Anesthesia awareness and the bispectral index. 22 Jul 2008
• General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. 21 Jun 2008
• Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol. 5 Jun 2008
• Effects of remifentanil-based general anaesthesia with propofol or sevoflurane on muscle microcirculation as assessed by near-infrared spectroscopy. Jun 2008
• Memory and awareness during anaesthesia. 30 May 2008
• An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function. 30 May 2008
• General anesthetics induce apoptotic neurodegeneration in the neonatal rat spinal cord. 30 May 2008
• Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain. 30 May 2008
• Roles of TRESK, a novel two-pore domain K+ channel, in pain pathway and general anesthesia. 30 May 2008
• Awareness with recall during general anaesthesia: a prospective observational evaluation of 4001 patients. 28 May 2008
• Intraoperative dreams reported after general anaesthesia are not early interpretations of delayed awareness. 10 May 2008
• BIS does not predict dreams reported after anaesthesia. 10 May 2008
• General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal. 29 Apr 2008

See a longer list of these articles.

Technical information about 'Anesthetics, General'

Definition: Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173)

Registry Number: 0

Descriptor UI: D018681

Alternative terms: Anesthetics, General; General Anesthetics;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.277.100.035; D27.505.954.427.210.100.035;

History Note: 95

Technical Notes: see note at ANESTHETICS