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Angiotensin-Converting Enzyme Inhibitors
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Definition of 'Angiotensin-Converting Enzyme Inhibitors'

A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.

Common names: Angiotensin-Converting Enzyme Inhibitors; Angiotensin Converting Enzyme Inhibitors; Antagonists, Angiotensin-Converting Enzyme; Antagonists, Angiotensin Converting Enzyme; Angiotensin I-Converting Enzyme Inhibitors; Angiotensin I Converting Enzyme Inhibitors

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Sunday, November 22, 2009

Strict blood-pressure control and progression of renal failure in children.

20 Oct 2009 BACKGROUND: Although inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney disease, the blood-pressure target for optimal renal protection is controversial. We assessed the long-term ... Read more...


Clinical benefit of early reperfusion therapy in patients with ST-elevation myocardial infarction usually excluded from randomized clinical trials (results from the Maximal Individual Therapy in Acute Myocardial Infarction Plus [MITRA Plus] registry).

13 Oct 2009 Randomized clinical trials (RCTs) usually enroll selected patient populations that may not be representative for patients seen in everyday practice. Therefore, concerns have been raised regarding their external validity. For the present study we ... Read more...


Proteinuria, chronic kidney disease, and the effect of an angiotensin receptor blocker in addition to an angiotensin-converting enzyme inhibitor in patients with moderate to severe heart failure.

3 Oct 2009 BACKGROUND: Chronic kidney disease (CKD) is an established risk factor for poor outcomes in heart failure (HF). Whether proteinuria provides additional prognostic information is not known. Renin-angiotensin blockade medications improve outcomes in ... Read more...

 

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Technical information about 'Angiotensin-Converting Enzyme Inhibitors'

Definition: A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.

Registry Number: 0

Descriptor UI: D000806

Alternative terms: Angiotensin-Converting Enzyme Inhibitors; Angiotensin Converting Enzyme Inhibitors; Antagonists, Angiotensin-Converting Enzyme; Antagonists, Angiotensin Converting Enzyme; Angiotensin I-Converting Enzyme Inhibitors; Angiotensin I Converting Enzyme Inhibitors; Inhibitors, Angiotensin-Converting Enzyme; Enzyme Inhibitors, Angiotensin-Converting; Inhibitors, Angiotensin Converting Enzyme; ACE Inhibitors; Kininase II Antagonists; Inhibitors, Kininase II; Kininase II Inhibitors; Inhibitors, ACE; Angiotensin-Converting Enzyme Antagonists; Angiotensin Converting Enzyme Antagonists; Enzyme Antagonists, Angiotensin-Converting; Antagonists, Kininase II;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.389.745.085;

Online Note: use TEPROTIDE to search ANGIOTENSIN I-CONVERTING ENZYME INHIBITOR 1991-93

History Note: 88; ANGIOTENSIN I-CONVERTING ENZYME INHIBITOR was see TEPROTIDE 1991-93

Technical Notes: protease inhib & antihypertensives; DF: ACE INHIB

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