Animal Use Alternatives - Research News and Information

Wednesday, January 07, 2009

Mucosal irritation potential of personal lubricants relates to product osmolality as detected by the slug mucosal irritation assay.

29 Apr 2008 BACKGROUND: The slug mucosal irritation assay has recently been used as a sensitive measure of mucus membrane tolerance for vaginal microbicide products and carriers. In the current study, it was determined whether musosal irritation potency of ... Read more...

[Importance of research on alternatives to animal experiments in pharmaceutical sciences]

29 Apr 2008 The Japanese animal protection law was amended in 2005 to include the 3Rs principle in animal experiments. According to this new law, the Ministry of Education, Culture, Sports, Science and Technology, the Ministry of Health, Labor and Welfare, and ... Read more...

[Alternatives to animal experimentation v.s. animal rights terrorism]

29 Apr 2008 Systematic modern animal experimentation was established by Bernard Claude who wrote "An Introduction to the Study of Experimental Medicine" in 1865. At this point, the public was already asking that the pain and distress of experimental animals be ... Read more...

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Latest indexed articles for 'Animal Use Alternatives'

These are the very latest articles for this heading:

• Switching swine for simulators: at what cost? 5 Oct 2008
• Medical schools swap pigs for plastic. 6 May 2008
• Mucosal irritation potential of personal lubricants relates to product osmolality as detected by the slug mucosal irritation assay. 29 Apr 2008
• Pushing the limits. 29 Apr 2008
• [Development of alternative animal experiments in pharmaceutical sciences] 29 Apr 2008
• [Importance of research on alternatives to animal experiments in pharmaceutical sciences] 29 Apr 2008
• [Alternatives to animal experimentation v.s. animal rights terrorism] 29 Apr 2008
• Directions in QSAR modeling for regulatory uses in OECD member countries, EU and in Russia. 30 Mar 2008
• Successful prevalidation of the slug mucosal irritation test to assess the eye irritation potency of chemicals. 2 Mar 2008
• Nonanimal alternatives for skin sensitization: a step forward? 28 Feb 2008
• Collaborative studies and animal reuse: one study, two institutions. 30 Jan 2008
• Collaborative studies and animal reuse. 30 Jan 2008
• Collaborative studies and animal reuse: the other IACUC should decide. 30 Jan 2008
• Collaborative studies and animal reuse: inter-related, not just related. 30 Jan 2008
• Collaborative studies and animal reuse: a word from OLAW and USDA. 30 Jan 2008
• Q & A: Frankie Trull. Interviewed by Genevive Bjorn. 30 Jan 2008
• Replication and the 3Rs: an interesting dialog. 30 Dec 2007
• Replication and the 3Rs. 30 Dec 2007
• Replication and the 3Rs: a word from USDA. 30 Dec 2007
• Replication and the 3Rs: a question of power or an abuse of power? 30 Dec 2007

See a longer list of these articles.

Technical information about 'Animal Use Alternatives'

Definition: Alternatives to the use of animals in research, testing, and education. The alternatives may include reduction in the number of animals used, replacement of animals with a non-animal model or with animals of a species lower phylogenetically, or refinement of methods to minimize pain and distress of animals used.

Descriptor UI: D023401

Alternative terms: Animal Use Alternatives; Alternative, Animal Use; Alternatives, Animal Use; Animal Use Alternative; Use Alternative, Animal; Use Alternatives, Animal;

Related Mesh Headings: Animal Welfare; Animal Experimentation;

Allowable Qualifiers: classification; economics; education; history; instrumentation; legislation & jurisprudence; manpower; methods; organization & administration; standards; trends; statistics & numerical data; ethics;

Tree Number: E05.017.080;

History Note: 2001