Anti-Inflammatory Agents, Non-Steroidal - Adverse effects
Research News and Information

Monday, November 23, 2009

Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses.

29 Sep 2009 OBJECTIVE: To investigate effects of lidocaine hydrochloride administered IV on mucosal inflammation in ischemia-injured jejunum of horses treated with flunixin meglumine. ANIMALS: 24 horses. PROCEDURES: Horses received saline (0.9% NaCl) solution ... Read more...

Bioequivalence study of low-dose diclofenac potassium tablet formulations.

29 Sep 2009 BACKGROUND AND AIM: Diclofenac is a nonsteroidal antiinflammatory drug with potent analgesic and anti-inflammatory properties. An immediate-release formulation containing a low dose of 12.5 mg diclofenac-potassium (-K) is marketed as over the ... Read more...

Prevalence of fatal adverse drug reactions in hospitalized patients.

29 Sep 2009 OBJECTIVE: The aims of the present study were to assess the prevalence of fatal adverse drug reactions (FADRs) in a hospitalized population, identify the drugs involved and investigate reported risk factors for these events. METHODS: The study ... Read more...

Latest indexed articles for 'Anti-Inflammatory Agents, Non-Steroidal - Adverse effects'

These are the very latest articles for this heading:

• Tom MacDonald replies to Marisa de Andrade. 19 Oct 2009
• Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses. 29 Sep 2009
• Bioequivalence study of low-dose diclofenac potassium tablet formulations. 29 Sep 2009
• Prevalence of fatal adverse drug reactions in hospitalized patients. 29 Sep 2009
• Infections in flares of inflammatory bowel disease. 29 Sep 2009
• Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization. 17 Sep 2009
• Research Ethics . In clear sight. 31 Aug 2009
• Mefenamic acid-induced bilateral transient myopia, secondary angle closure glaucoma and choroidal detachment. 30 Aug 2009
• Trends and determinants of adequate gastroprotection in patients chronically using NSAIDs. 30 Aug 2009
• Upper gastrointestinal tract bleeding in Ilorin, Nigeria--a report of 30 cases. 30 Aug 2009
• Clinical characteristics and risk factors of colistin-induced nephrotoxicity. 30 Aug 2009
• Nepafenac-associated bilateral corneal melt after photorefractive keratectomy. 30 Aug 2009
• Helicobacter pylori and non-malignant diseases. 30 Aug 2009
• Treatment of neuromyelitis optica with mycophenolate mofetil: retrospective analysis of 24 patients. 30 Aug 2009
• Ketorolac tromethamine formulations: an overview. 30 Aug 2009
• Excessive acute migraine medication use and migraine progression. 30 Aug 2009
• Use of clofazimine in dermatology. 30 Aug 2009
• Exacerbation of inflammatory bowel diseases associated with the use of nonsteroidal anti-inflammatory drugs: myth or reality? 25 Aug 2009
• [Chronic musculo-skeletal pain in Switzerland: patient care from the view of physicians and patients] 24 Aug 2009
• [Therapy of joint pain in arthrosis and arthritis. Classical nonsteroidal anti-inflammatory agents, coxibs--or opioids?] 18 Aug 2009

See a longer list of these articles.

Technical information about 'Anti-Inflammatory Agents, Non-Steroidal'

Definition: Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)

Registry Number: 0

Descriptor UI: D000894

Alternative terms: Anti-Inflammatory Agents, Non-Steroidal; Anti Inflammatory Agents, Non Steroidal; Anti Inflammatory Agents, Nonsteroidal; NSAIDs; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Agents, Nonsteroidal Antiinflammatory; Nonsteroidal Antiinflammatory Agents; Non-Steroidal Anti-Inflammatory Agents; Agents, Non-Steroidal Anti-Inflammatory; Non Steroidal Anti Inflammatory Agents; Nonsteroidal Anti-Inflammatory Agents; Agents, Nonsteroidal Anti-Inflammatory; Anti-Inflammatory Agents, Nonsteroidal; Nonsteroidal Anti Inflammatory Agents; Anti-Rheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Anti-Rheumatic; Anti Rheumatic Agents, Non Steroidal; Non-Steroidal Anti-Rheumatic Agents; Antirheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Antirheumatic; Antirheumatic Agents, Non Steroidal; Non-Steroidal Antirheumatic Agents; Aspirin-Like Agents; Agents, Aspirin-Like; Aspirin Like Agents; Analgesics, Anti-Inflammatory; Analgesics, Anti Inflammatory; Anti-Inflammatory Analgesics;

Related Mesh Headings: Cyclooxygenase Inhibitors;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.850.014.040.500; D27.505.954.158.030; D27.505.954.329.030;

Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89

History Note: 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89

Technical Notes: GEN or unspecified: prefer specifics; DF: NSAID