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Anti-Inflammatory Agents, Non-Steroidal - Therapeutic use
Research News and Information
Definition of 'Anti-Inflammatory Agents, Non-Steroidal'Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5) |
Saturday, November 21, 2009
28 Dec 2009
BACKGROUND: Opioids continue to remain the primary analgesics in children undergoing ophthalmic surgery, and their use may be associated with adverse effects like vomiting and respiratory depression. Topical anesthesia avoids these adverse effects ... Read more...
Fibromyalgia comorbidity in primary headaches.
13 Dec 2009
Fibromyalgia syndrome (FMS) is a chronic pain condition of unknown aetiology characterized by diffuse pain and tenderness at tender points. The aim of the study was to assess the prevalence and clinical features of FMS in the different forms of ... Read more...
6 Dec 2009
The main objective of this study was to determine whether elevated blood beta-amyloid (Abeta) levels among the first-degree relatives of patients with Alzheimer's Disease (AD) are associated with vascular risk factors of AD. Serum Abeta was measured ... Read more...
Latest indexed articles for 'Anti-Inflammatory Agents, Non-Steroidal - Therapeutic use'
These are the very latest articles for this heading:
- Comparison of topical lignocaine gel and fentanyl for perioperative analgesia in children undergoing cataract surgery.
28 Dec 2009 - Fibromyalgia comorbidity in primary headaches.
13 Dec 2009 - High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients.
6 Dec 2009 - Management of osteoblastoma and osteoid osteoma of the spine in childhood.
30 Oct 2009 - Teaching NeuroImages: synovial cyst: a cause of low back pain.
11 Oct 2009 - Correlation between anti-fibrotic effect of baicalin and serum cytokines in rat hepatic fibrosis.
5 Oct 2009 - Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae).
29 Sep 2009 - Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis.
29 Sep 2009 - Delayed onset nodules from liquid injectable silicone: report of a case, evaluation of associated histopathology and results of treatment with minocycline and celocoxib.
29 Sep 2009 - Successful treatment of pemphigus vulgaris with etanercept in four patients.
29 Sep 2009 - Henoch-Schönlein purpura.
29 Sep 2009 - Infections in flares of inflammatory bowel disease.
29 Sep 2009 - Surgery versus non-surgical therapy for carpal tunnel syndrome: a randomised parallel-group trial.
24 Sep 2009 - Incorporating multiple interventions in meta-analysis: an evaluation of the mixed treatment comparison with the adjusted indirect comparison.
19 Sep 2009 - Should aspirin be used for the primary prevention of cardiovascular disease in people with diabetes?
19 Sep 2009 - Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model.
14 Sep 2009 - Patient information. Costochondritis: what you need to know.
13 Sep 2009 - Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis.
13 Sep 2009 - Targeting NF-kappa B with a natural triterpenoid alleviates skin inflammation in a mouse model of psoriasis.
12 Sep 2009 - [Osteoporosis pain management]
9 Sep 2009
See a longer list of these articles.
Technical information about 'Anti-Inflammatory Agents, Non-Steroidal'
Definition: Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
Registry Number: 0
Descriptor UI: D000894
Alternative terms: Anti-Inflammatory Agents, Non-Steroidal; Anti Inflammatory Agents, Non Steroidal; Anti Inflammatory Agents, Nonsteroidal; NSAIDs; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Agents, Nonsteroidal Antiinflammatory; Nonsteroidal Antiinflammatory Agents; Non-Steroidal Anti-Inflammatory Agents; Agents, Non-Steroidal Anti-Inflammatory; Non Steroidal Anti Inflammatory Agents; Nonsteroidal Anti-Inflammatory Agents; Agents, Nonsteroidal Anti-Inflammatory; Anti-Inflammatory Agents, Nonsteroidal; Nonsteroidal Anti Inflammatory Agents; Anti-Rheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Anti-Rheumatic; Anti Rheumatic Agents, Non Steroidal; Non-Steroidal Anti-Rheumatic Agents; Antirheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Antirheumatic; Antirheumatic Agents, Non Steroidal; Non-Steroidal Antirheumatic Agents; Aspirin-Like Agents; Agents, Aspirin-Like; Aspirin Like Agents; Analgesics, Anti-Inflammatory; Analgesics, Anti Inflammatory; Anti-Inflammatory Analgesics;
Related Mesh Headings: Cyclooxygenase Inhibitors;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D27.505.696.663.850.014.040.500; D27.505.954.158.030; D27.505.954.329.030;
Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89
History Note: 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89
Technical Notes: GEN or unspecified: prefer specifics; DF: NSAID