Anti-Inflammatory Agents, Non-Steroidal - Research News and Information

Wednesday, January 07, 2009

Ginsenosides chemistry, biosynthesis, analysis, and potential health effects.

30 Dec 2008 Ginsenosides are a special group of triterpenoid saponins that can be classified into two groups by the skeleton of their aglycones, namely dammarane- and oleanane-type. Ginsenosides are found nearly exclusively in Panax species (ginseng) and up to ... Read more...

Bartter syndrome presenting as poor weight gain and abdominal mass in an infant.

29 Nov 2008 Bartter syndrome, a group of disorders that encompasses multiple genetic defects with similar clinical presentation, has been divided into six different genotypes, according to different genetic defects, and into three main clinical variants (or ... Read more...

15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.

30 Oct 2008 We previously demonstrated that, in the MC615 cartilage cell line, the p38/NF-kB pathway is activated both during differentiation and in response to an inflammatory stimulus. In both cases, the p38/NF-kB pathway activation leads to the expression ... Read more...

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Latest indexed articles for 'Anti-Inflammatory Agents, Non-Steroidal'

These are the very latest articles for this heading:

• Ginsenosides chemistry, biosynthesis, analysis, and potential health effects. 30 Dec 2008
• Bartter syndrome presenting as poor weight gain and abdominal mass in an infant. 29 Nov 2008
• 15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. 30 Oct 2008
• Effects of non-selective non-steroidal anti-inflammatory drugs on the aggressiveness of prostate cancer. 30 Oct 2008
• When there is smoke, there may be fire: functional abdominal pain and the role of inflammation. 30 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Acetaminophen poisoning. 28 Oct 2008
• Interpreting research findings to guide treatment in practice. 22 Oct 2008
• Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen: results from the 2001-2002 National Health and Nutrition Examination Survey. 13 Oct 2008
• S-nitrosylated S100A8: novel anti-inflammatory properties. 13 Oct 2008
• The editor's roundtable: nonsteroidal antiinflammatory drugs and cardiovascular risk. 13 Oct 2008
• Hunter-killer peptide (HKP) for targeted therapy. 7 Oct 2008
• [Do women with Caesarean section have to choose between pain relief and breastfeeding?] 7 Oct 2008
• Modulation of breast cancer risk by nonsteroidal anti-inflammatory drugs. 5 Oct 2008
• Breast cancer and use of nonsteroidal anti-inflammatory drugs: a meta-analysis. 5 Oct 2008
• Anti-inflammatory cembranoids from the soft corals Sinularia querciformis and Sinularia granosa. Oct 2008

See a longer list of these articles.

Technical information about 'Anti-Inflammatory Agents, Non-Steroidal'

Definition: Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)

Registry Number: 0

Descriptor UI: D000894

Alternative terms: Anti-Inflammatory Agents, Non-Steroidal; Anti Inflammatory Agents, Non Steroidal; Anti Inflammatory Agents, Nonsteroidal; NSAIDs; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Agents, Nonsteroidal Antiinflammatory; Nonsteroidal Antiinflammatory Agents; Non-Steroidal Anti-Inflammatory Agents; Agents, Non-Steroidal Anti-Inflammatory; Non Steroidal Anti Inflammatory Agents; Nonsteroidal Anti-Inflammatory Agents; Agents, Nonsteroidal Anti-Inflammatory; Anti-Inflammatory Agents, Nonsteroidal; Nonsteroidal Anti Inflammatory Agents; Anti-Rheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Anti-Rheumatic; Anti Rheumatic Agents, Non Steroidal; Non-Steroidal Anti-Rheumatic Agents; Antirheumatic Agents, Non-Steroidal; Agents, Non-Steroidal Antirheumatic; Antirheumatic Agents, Non Steroidal; Non-Steroidal Antirheumatic Agents; Aspirin-Like Agents; Agents, Aspirin-Like; Aspirin Like Agents; Analgesics, Anti-Inflammatory; Analgesics, Anti Inflammatory; Anti-Inflammatory Analgesics;

Related Mesh Headings: Cyclooxygenase Inhibitors;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.850.014.040.500; D27.505.954.158.030; D27.505.954.329.030;

Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89

History Note: 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89

Technical Notes: GEN or unspecified: prefer specifics; DF: NSAID