Antibodies, Antinuclear - Research News and Information

Wednesday, January 07, 2009

Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice.

13 Oct 2008 Autoantigen presentation to T cells is crucial for the development of autoimmune disease. However, the mechanisms of autoantigen presentation are poorly understood. In this study, we show that splenic phagocytes play an important role in ... Read more...

Prevalence and patterns of anti-nuclear antibodies in Korean children with juvenile idiopathic arthritis according to ILAR criteria.

30 Aug 2008 OBJECTIVES: To investigate the prevalence and patterns of anti-nuclear antibodies (ANA) in different subtypes of juvenile idiopathic arthritis (JIA) according to the International League of Associations for Rheumatology (ILAR) criteria. METHODS: ... Read more...

Pineal parenchymal tumors--utility of immunohistochemical markers in prognostication.

30 Aug 2008 BACKGROUND AND OBJECTIVE: The pineal parenchymal tumors are rare, comprising 15-30% of all tumors of pineal region. Their histological classification alone has been found to be inadequate for prognostication. Hence, we correlated their ... Read more...

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Latest indexed articles for 'Antibodies, Antinuclear'

These are the very latest articles for this heading:

• Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice. 13 Oct 2008
• Prevalence and patterns of anti-nuclear antibodies in Korean children with juvenile idiopathic arthritis according to ILAR criteria. 30 Aug 2008
• Pineal parenchymal tumors--utility of immunohistochemical markers in prognostication. 30 Aug 2008
• Effects of olopatadine in limited scleroderma with peripheral eosinophils. 30 Aug 2008
• Prognosis of neonates in pregnant women with systemic lupus erythematosus. 28 Aug 2008
• Glatiramer acetate treatment does not modify the clinical course of (NZB x BXSB)F1 lupus murine model. 4 Aug 2008
• Effect of anti-CD134L mAb and CTLA4Ig on ConA-induced proliferation, Th cytokine secretion, and anti-dsDNA antibody production in spleen cells from lupus-prone BXSB mice. 30 Jul 2008
• Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome. 30 Jul 2008
• Prevalence and clinical associations of anti-Ku antibodies in systemic autoimmune diseases. 30 Jul 2008
• Autoantibodies and their significance in myositis. 30 Jul 2008
• One question on the work on antinuclear antibody levels in patients with Hodgkin's and non-Hodgkin's lymphoma. 30 Jul 2008
• Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients. 30 Jul 2008
• Positive direct immunofluorescence and autoantibody profiles in psoriasis patients. 30 Jul 2008
• The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. 22 Jul 2008
• Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus. 13 Jul 2008
• Polymorphism in the 5' regulatory region of the B-lymphocyte activating factor gene is associated with the Ro/La autoantibody response and serum BAFF levels in primary Sjogren's syndrome. 8 Jul 2008
• Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus. 29 Jun 2008
• Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus. 29 Jun 2008
• Tacrolimus for antisynthetase syndrome with interstitial lung disease? 29 Jun 2008
• Ocular manifestations in a case of childhood cicatricial pemphigoid. 29 Jun 2008

See a longer list of these articles.

Technical information about 'Antibodies, Antinuclear'

Definition: Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

Registry Number: 0

Descriptor UI: D000974

Alternative terms: Antibodies, Antinuclear; Antinuclear Factors; Factors, Antinuclear; Antinuclear Factor; Factor, Antinuclear; Antinuclear Antibodies; Antinuclear Antibody; Antibody, Antinuclear; Fluorescent Antinuclear Antibodies; Antibodies, Fluorescent Antinuclear; Antinuclear Antibodies, Fluorescent; Antibodies, Anti-DNA; Antibodies, Anti DNA; Anti-DNA Antibodies; Anti DNA Antibodies;

Related Mesh Headings: Collagen Diseases;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114.323.204; D12.776.124.790.651.114.323.204; D12.776.377.715.548.114.323.204;

Online Note: use ANTIBODIES, ANTINUCLEAR to search ANTINUCLEAR FACTORS 1966-89 (Prov 1966-69)

History Note: 90; was ANTINUCLEAR FACTORS 1966-89 (Prov 1966-69)

Technical Notes: coordinate with specific nuclear antigen; do not coordinate with ANTIBODY FORMATION for /biosyn