Antibodies
Research News and Information

Monday, November 23, 2009

The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.

21 Dec 2009 BACKGROUND: The JAL antigen (Rh48) was discovered more than 30 years ago when it caused hemolytic disease of the fetus and newborn in an African American family. A decade later it was found to cause hemolytic disease of the fetus and newborn in a ... Read more...

Positive direct and indirect antiglobulin tests associated with oxaliplatin can be due to drug antibody and/or drug-induced nonimmunologic protein adsorption.

13 Dec 2009 BACKGROUND: Two patients were suspected of having immune hemolytic anemia (IHA) due to oxaliplatin. A related drug, cisplatin, is known to cause nonimmunologic protein adsorption (NIPA). Studies were performed to determine the presence of ... Read more...

Effect of neutralizing antibodies on biomarker responses to interferon beta: the INSIGHT study.

Nov 2009 BACKGROUND: Interferon beta (IFNbeta) effectively reduces disease activity in patients with multiple sclerosis (MS). Neutralizing antibodies (NAbs) can diminish or abolish the clinical efficacy of IFNbeta therapies. Biomarkers of the IFNbeta ... Read more...

Latest indexed articles for 'Antibodies'

These are the very latest articles for this heading:

• The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp. 21 Dec 2009
• Positive direct and indirect antiglobulin tests associated with oxaliplatin can be due to drug antibody and/or drug-induced nonimmunologic protein adsorption. 13 Dec 2009
• Is immunization necessary after therapy for acute lymphoblastic leukemia (ALL) has been completed? 29 Nov 2009
• Effect of neutralizing antibodies on biomarker responses to interferon beta: the INSIGHT study. Nov 2009
• Effect of anti-IFN{beta} antibodies on MRI lesions of MS patients in the BECOME study. Nov 2009
• Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold. 30 Oct 2009
• C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin. 30 Oct 2009
• A confirmation study of Russian and Ukrainian data on effects of 2450 MHz microwave exposure on immunological processes and teratology in rats. 30 Oct 2009
• Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion. 13 Oct 2009
• Cutting Edge: Tumor-specific CD8+ T cells infiltrating prostatic tumors are induced to become suppressor cells. 13 Oct 2009
• Cell-targeted self-assembled DNA nanostructures. 12 Oct 2009
• Antibody profiling by Luciferase Immunoprecipitation Systems (LIPS). 5 Oct 2009
• Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes. 4 Oct 2009
• Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion. 29 Sep 2009
• PolyI:C plus IL-2 or IL-12 induce IFN-gamma production by human NK cells via autocrine IFN-beta. 29 Sep 2009
• Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE. 29 Sep 2009
• Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor. 29 Sep 2009
• Nature of "Tau" immunoreactivity in normal myonuclei and inclusion body myositis. 29 Sep 2009
• Effects of different levels of vitamin E on growth performance and immune responses of broilers under heat stress. 29 Sep 2009
• Anomalous immunogenic properties of serine proteases. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Antibodies'

Definition: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Registry Number: 0

Descriptor UI: D000906

Alternative terms: Antibodies;

Related Mesh Headings: Antigen-Antibody Reactions;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Pharmacological Action: Immunologic Factors;

Tree Number: D12.776.124.486.485.114; D12.776.124.790.651.114; D12.776.377.715.548.114;

Online Note: pre-explosion = ANTIBODIES (PX)

Technical Notes: antibodies to IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; etc. = ANTIBODIES, ANTI-IDIOTYPIC (IM) + IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; etc. (IM); ANTIBODY-TOXIN CONJUGATES is available as toxin carrier: see note there