Antibody Specificity
Research News and Information

Sunday, November 22, 2009

A human domain antibody and Lewis b glycoconjugate that inhibit binding of Helicobacter pylori to Lewis b receptor and adhesion to human gastric epithelium.

13 Nov 2009 Increasing antibiotic resistance has prompted development of alternative approaches to antimicrobial therapy, including blocking microbial adhesion to host receptors. The BabA adhesin of Helicobacter pylori binds to fucosylated blood group antigens, ... Read more...

The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I.

29 Sep 2009 Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound ... Read more...

Nature of "Tau" immunoreactivity in normal myonuclei and inclusion body myositis.

29 Sep 2009 Sarcoplasmic accumulation of phosphorylated-tau has been widely stated to occur in and contribute to the pathogenesis of muscle disease in inclusion body myositis. Twenty inflammatory myopathy and 10 normal muscle samples along with a range of other ... Read more...

Latest indexed articles for 'Antibody Specificity'

These are the very latest articles for this heading:

• A human domain antibody and Lewis b glycoconjugate that inhibit binding of Helicobacter pylori to Lewis b receptor and adhesion to human gastric epithelium. 13 Nov 2009
• The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I. 29 Sep 2009
• Nature of "Tau" immunoreactivity in normal myonuclei and inclusion body myositis. 29 Sep 2009
• Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor cells. 19 Sep 2009
• Antibody expressing pea seeds as fodder for prevention of gastrointestinal parasitic infections in chickens. 9 Sep 2009
• Adenylyl cyclase type 5 protein expression during cardiac development and stress. 2 Sep 2009
• HIV/AIDS research. Potent HIV antibodies spark vaccine hopes. 2 Sep 2009
• Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue. 30 Aug 2009
• The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. 29 Aug 2009
• A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis. 29 Aug 2009
• DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge. 26 Aug 2009
• HLA-specific antibodies developed in the first year posttransplant are predictive of chronic rejection and renal graft loss. 25 Aug 2009
• The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators. 18 Aug 2009
• Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a. 15 Aug 2009
• A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood. 14 Aug 2009
• DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage. 11 Aug 2009
• Autoantibodies and their antigens in autoimmune hepatitis. 10 Aug 2009
• The contribution of naturally occurring IgM antibodies, IgM cross-reactivity and complement dependency in murine humoral responses to pneumococcal capsular polysaccharides. 2 Aug 2009
• Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32. Aug 2009
• Redox-reactive autoantibodies: biochemistry, characterization, and specificities. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Antibody Specificity'

Definition: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.

Descriptor UI: D000918

Alternative terms: Antibody Specificity; Antibody Specificities; Specificities, Antibody; Specificity, Antibody;

Related Mesh Headings: Antibodies, Bispecific; T-Cell Antigen Receptor Specificity;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G12.100;

History Note: 72(70)

Technical Notes: coord IM with specific antibody (IM)