Antidepressive Agents, Second-Generation
Research News and Information

Sunday, November 22, 2009

Effects of Lorazepam and citalopram on human defensive reactions: ethopharmacological differentiation of fear and anxiety.

5 Oct 2009 Drugs that are clinically effective against generalized anxiety disorder preferentially alter rodent risk assessment behavior, whereas drugs that are clinically effective against panic disorder preferentially alter rodent flight behavior. The ... Read more...

Pharmacotherapy for depressed pregnant women: overcoming obstacles to gathering essential data.

29 Sep 2009 Approximately 3% of pregnant women take antidepressant medications. Information on the impact of antidepressants on short- and long-term maternal and offspring outcomes is highly desirable but neglected. The position that the dearth of treatment ... Read more...

The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.

29 Sep 2009 BACKGROUND: Antidepressant drugs act as potent inhibitors of norepinephrine and/or serotonin reuptake and are widely used with opioids for the treatment of chronic pain. The mechanism of this increased analgesic action is unclear. We compared the ... Read more...

Latest indexed articles for 'Antidepressive Agents, Second-Generation'

These are the very latest articles for this heading:

• Making the best use of available evidence: the case of new generation antidepressants: a response to: are all antidepressants equal? 30 Oct 2009
• Are all antidepressants equal? 30 Oct 2009
• GlaxoSmithKline told to pay family $2.5m after jury finds paroxetine caused son's heart defects. 13 Oct 2009
• GSK is sued in US over alleged link of paroxetine to birth defects. 10 Oct 2009
• Effects of Lorazepam and citalopram on human defensive reactions: ethopharmacological differentiation of fear and anxiety. 5 Oct 2009
• Pharmacotherapy for depressed pregnant women: overcoming obstacles to gathering essential data. 29 Sep 2009
• Benefits exceed risks of newer antidepressant medications in youth--maybe not. 29 Sep 2009
• Benefits exceed risks of newer antidepressant medications in youth--maybe. 29 Sep 2009
• The synergistic interaction between morphine and maprotiline after intrathecal injection in rats. 29 Sep 2009
• [Pharmaceutical treatment of cancer-associated fatigue--a survey of a Cochrane review] 19 Sep 2009
• Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats. 14 Sep 2009
• Venlafaxine-associated tinnitus. 13 Sep 2009
• Impacts of switching antidepressants after successful electroconvulsive therapy on the maintenance of clinical remission in patients with treatment-resistant depression: a chart review. 30 Aug 2009
• Antidepressant medication use during breastfeeding. 30 Aug 2009
• Restraint, hunger, and disinhibition following treatment for binge-eating disorder. 30 Aug 2009
• Bupropion-induced neck and shoulder pain. 30 Aug 2009
• Imbalance between pro- and anti-inflammatory cytokines, and between Th1 and Th2 cytokines in depressed patients: the effect of electroacupuncture or fluoxetine treatment. 30 Aug 2009
• The role of serotonin in nonnormative risky choice: the effects of tryptophan supplements on the "reflection effect" in healthy adult volunteers. 30 Aug 2009
• Fluoxetine and olanzapine combination therapy in treatment-resistant major depression: review of efficacy and safety data. 30 Aug 2009
• Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder. 24 Aug 2009

See a longer list of these articles.

Technical information about 'Antidepressive Agents, Second-Generation'

Definition: A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake.

Registry Number: 0

Descriptor UI: D018687

Alternative terms: Antidepressive Agents, Second-Generation; Antidepressive Agents, Second Generation; Antidepressive Drugs, Second-Generation; Antidepressive Drugs, Second Generation; Drugs, Second-Generation Antidepressive; Second-Generation Antidepressive Drugs; Atypical Antidepressants; Second-Generation Antidepressive Agents; Agents, Second-Generation Antidepressive; Second Generation Antidepressive Agents; Antidepressants, Atypical;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.427.700.122.050;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics