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Antidepressive Agents, Tricyclic - Adverse effects
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Definition of 'Antidepressive Agents, Tricyclic'

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

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Monday, November 23, 2009

[Benzodiazepine reduction does not imply an increased consumption of antidepressants. A survey of two medical practices]

3 Oct 2009 INTRODUCTION: The consumption of benzodiazepines (BZ) and cyclopyrrolones (CP) has attracted great interest in recent years due to the serious side-effects associated with these drugs. Two medical practices introduced a more restrictive approach to ... Read more...


Treatment-resistant depression.

13 Jul 2009 Up to two thirds of patients with major unipolar depression will not respond to the first medication prescribed. Depression may be considered resistant to treatment when at least two trials with antidepressants from different pharmacologic classes ... Read more...


New onset somnambulism associated with different dosage of mirtazapine: a case report.

29 Jun 2009 Somnambulism consists of variously complex behaviors that may result in harm to self or to others. Many different medications have been reported to induce somnambulism, and a few of them are newer antidepressants. A 40-year-old woman with history of ... Read more...

 

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Technical information about 'Antidepressive Agents, Tricyclic'

Definition: Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

Registry Number: 0

Descriptor UI: D000929

Alternative terms: Antidepressive Agents, Tricyclic; Antidepressant Drugs, Tricyclic; Drugs, Tricyclic Antidepressant; Tricyclic Antidepressant Drugs; Antidepressants, Tricyclic; Tricyclic Antidepressants; Tricyclic Antidepressive Agents; Agents, Tricyclic Antidepressive;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.427.700.122.055;

History Note: 75

Technical Notes: GEN or unspecified; prefer specifics

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