Antidepressive Agents, Tricyclic
Research News and Information

Saturday, November 21, 2009

[Narcolepsy and other hypersomnias]

6 Oct 2009 BACKGROUND: Narcolepsy is currently categorized into three groups; narcolepsy with and without emotionally triggered loss of muscle tone (cataplexy), and narcolepsy secondary to other medical conditions. Many patients with hypersomnia are diagnosed ... Read more...

[Benzodiazepine reduction does not imply an increased consumption of antidepressants. A survey of two medical practices]

3 Oct 2009 INTRODUCTION: The consumption of benzodiazepines (BZ) and cyclopyrrolones (CP) has attracted great interest in recent years due to the serious side-effects associated with these drugs. Two medical practices introduced a more restrictive approach to ... Read more...

Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial.

28 Sep 2009 BACKGROUND: Drugs for neuropathic pain have incomplete efficacy and dose-limiting side-effects when given as monotherapy. We assessed the efficacy and tolerability of combined nortriptyline and gabapentin compared with each drug given alone. ... Read more...

Latest indexed articles for 'Antidepressive Agents, Tricyclic'

These are the very latest articles for this heading:

• [Narcolepsy and other hypersomnias] 6 Oct 2009
• [Benzodiazepine reduction does not imply an increased consumption of antidepressants. A survey of two medical practices] 3 Oct 2009
• You're the flight surgeon. Concussion and post-concussion syndrome. 29 Sep 2009
• Neuropathic pain treatment: a further step forward. 28 Sep 2009
• Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial. 28 Sep 2009
• Desipramine induces disorder in cholesterol-rich membranes: implications for viral trafficking. 8 Sep 2009
• Impacts of switching antidepressants after successful electroconvulsive therapy on the maintenance of clinical remission in patients with treatment-resistant depression: a chart review. 30 Aug 2009
• [Obsessive compulsive disorder (OCD)] 24 Aug 2009
• Mirtazapine versus venlafaxine for the treatment of somatic symptoms associated with major depressive disorder: a randomized, open-labeled trial. 17 Aug 2009
• Preparation of a poly(N-isopropylacrylamide-co-ethylene dimethacrylate) monolithic capillary and its application for in-tube solid-phase microextraction coupled to high-performance liquid chromatography. 30 Jul 2009
• Moving from tube to oral feeding in medically fragile nonverbal toddlers. 30 Jul 2009
• Selective serotonin reuptake inhibitor-induced spermatorrhea in 2 patients. 30 Jul 2009
• Fibromyalgia: poorly understood; treatments are disappointing. 30 Jul 2009
• Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes. 27 Jul 2009
• Treatment-resistant depression. 13 Jul 2009
• Antidepressants versus placebo for depression in primary care. 6 Jul 2009
• An open-label study of mirtazapine as treatment for combat-related PTSD. 5 Jul 2009
• [Post-surgical neuropathic pain] 29 Jun 2009
• First-line pharmacotherapies for depression - what is the best choice? 29 Jun 2009
• Evaluation of the levator ani and pelvic wall muscles in levator ani syndrome. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Antidepressive Agents, Tricyclic'

Definition: Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

Registry Number: 0

Descriptor UI: D000929

Alternative terms: Antidepressive Agents, Tricyclic; Antidepressant Drugs, Tricyclic; Drugs, Tricyclic Antidepressant; Tricyclic Antidepressant Drugs; Antidepressants, Tricyclic; Tricyclic Antidepressants; Tricyclic Antidepressive Agents; Agents, Tricyclic Antidepressive;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.427.700.122.055;

History Note: 75

Technical Notes: GEN or unspecified; prefer specifics