Antigens, CD147
Research News and Information

Monday, November 23, 2009

Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients.

13 Oct 2009 Expression of caveolin-1 (Cav-1) and extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) and their prognostic significance were analyzed in archive NPC samples. Cav-1 and CD147 were overexpressed in 49.48% (96/194) and 59.39% (117/197) of ... Read more...

Comprehensive profiling of the cell surface proteome of Sy5Y neuroblastoma cells yields a subset of proteins associated with tumor differentiation.

30 Jul 2009 Neuroblastoma tumors are derived from the neural crest and exhibit substantial phenotypic heterogeneity and various degrees of differentiation and maturation. The identification of new cell surface markers in neuroblastoma has relevance to disease ... Read more...

CD147 and VEGF expression in advanced renal cell carcinoma and their prognostic value.

30 Jul 2009 AIM: To investigate the clinicopathologic characteristics of extracellular matrix (ECM) metalloproteinase inducer (CD147) and vascular endothelial growth factor (VEGF) expression in advanced renal cell carcinoma (RCC), and to evaluate the clinical ... Read more...

Latest indexed articles for 'Antigens, CD147'

These are the very latest articles for this heading:

• Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients. 13 Oct 2009
• Comprehensive profiling of the cell surface proteome of Sy5Y neuroblastoma cells yields a subset of proteins associated with tumor differentiation. 30 Jul 2009
• CD147 and VEGF expression in advanced renal cell carcinoma and their prognostic value. 30 Jul 2009
• The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer. 19 Jul 2009
• Morphological changes and molecular expressions of hepatocellular carcinoma cells in three-dimensional culture model. 13 Jul 2009
• Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration. 24 Jun 2009
• A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity. 23 Jun 2009
• Anti-EMMPRIN monoclonal antibody as a novel agent for therapy of head and neck cancer. 7 Jun 2009
• CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. 5 Jun 2009
• Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A. Jun 2009
• Human T-leukemia and T-lymphoma express glutamate receptor AMPA GluR3, and the neurotransmitter glutamate elevates the cancer-related matrix-metalloproteinases inducer CD147/EMMPRIN, MMP-9 secretion and engraftment of T-leukemia in vivo. 30 May 2009
• The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion. 12 May 2009
• Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis. 6 May 2009
• Identification of an active site of EMMPRIN for the augmentation of matrix metalloproteinase-1 and -3 expression in a co-culture of human uterine cervical carcinoma cells and fibroblasts. 6 May 2009
• HAb18G (CD147), a cancer-associated biomarker and its role in cancer detection. 29 Apr 2009
• Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro. 29 Apr 2009
• Expression of CD147 on phorbol-12-myristate-13-acetate (PMA)-treated U937 cells differentiating into foam cells. 29 Apr 2009
• Expression of extracellular matrix metalloproteinase inducer and enhancement of the production of matrix metalloproteinase-1 in tongue squamous cell carcinoma. 13 Apr 2009
• EMMPRIN expression in tongue squamous cell carcinoma. 11 Apr 2009
• EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Antigens, CD147'

Definition: A widely distributed cell surface transmembrane glycoprotein that stimulates the synthesis of MATRIX METALLOPROTEINASES. It is found at high levels on the surface of malignant NEOPLASMS and may play a role as a mediator of malignant cell behavior.

Registry Number: 136894-56-9

Descriptor UI: D051926

Alternative terms: Antigens, CD147; Basigin Protein; CD147 Antigen; Antigen, CD147; Emmprin Protein; Extracellular Matrix Metalloproteinase Inducer (EMMPRIN); CD147 Antigens; Basigin; Emmprin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D12.776.395.550.045; D12.776.543.550.188; D23.050.285.040; D23.050.301.264.035.247; D23.101.100.110.247;

History Note: 2006(1990)