Antigens, Differentiation - Metabolism
Research News and Information

Monday, November 23, 2009

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.

13 Oct 2009 Pigment epithelium isolated from the eye possesses immunosuppressive properties such as regulatory T (Treg) cell induction; e.g., cultured retinal pigment epithelium (RPE) converts CD4(+) T cells into Treg cells in vitro. RPE constitutively ... Read more...

The basophil activation test in immediate-type drug allergy.

30 Jul 2009 Diagnosis of drug allergy involves first the recognition of sometimes unusual symptoms as drug allergy and, second, the identification of the eliciting drug. This is an often difficult task, as the clinical picture and underlying pathomechanisms are ... Read more...

Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo.

30 Jul 2009 Cutaneous melanoma is the most aggressive skin cancer; it is highly metastatic and responds poorly to current therapies. The expression of platelet-derived growth factor receptors (PDGF-Rs) is reported to be reduced in metastatic melanoma compared ... Read more...

Latest indexed articles for 'Antigens, Differentiation - Metabolism'

These are the very latest articles for this heading:

• Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions. 13 Oct 2009
• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. 30 Jul 2009
• Isolation of dendritic cells. 30 Jul 2009
• Structure of signal-regulatory protein alpha: a link to antigen receptor evolution. 21 Jul 2009
• Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy. 15 Jul 2009
• Turn-over of meningeal and perivascular macrophages in the brain of MCP-1-, CCR-2- or double knockout mice. 13 Jul 2009
• Hematopoietic stem cell origin of adipocytes. 30 Jun 2009
• Endocardial cells are a distinct endothelial lineage derived from Flk1+ multipotent cardiovascular progenitors. 29 Jun 2009
• Role of ocular pigment epithelial cells in immune privilege. 29 Jun 2009
• Effects of pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 in radiation-induced intestinal injury. 29 Jun 2009
• HPV16 tumor associated macrophages suppress antitumor T cell responses. 21 Jun 2009
• c-Maf is essential for the F4/80 expression in macrophages in vivo. 15 Jun 2009
• Roles of PU.1 in monocyte- and mast cell-specific gene regulation: PU.1 transactivates CIITA pIV in cooperation with IFN-gamma. 3 Jun 2009
• Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver. 30 May 2009
• Investigation of the chemical-induced selective type II (T(H)2) allergic response in mice: effect of the length of the sensitizing phase. 30 May 2009
• Ovarian cancer-derived glycodelin impairs in vitro dendritic cell maturation. 30 May 2009
• Ganoderma lucidum induces the expression of CD40/CD86 on peripheral blood monocytes. 30 May 2009
• The effects of Candida albicans cell wall protein fraction on dendritic cell maturation. 30 May 2009
• The antifibrogenic effect of hepatocyte growth factor (HGF) on renal tubular (HK-2) cells is dependent on cell growth. 30 May 2009

See a longer list of these articles.

Technical information about 'Antigens, Differentiation'

Definition: Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.

Registry Number: 0

Descriptor UI: D000943

Alternative terms: Antigens, Differentiation; Differentiation Markers; Markers, Differentiation; Differentiation Antigens; Marker Antigens; Antigens, Marker; Leu Antigens; Antigens, Leu; Differentiation Antigens, Hairy Cell Leukemia;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D23.050.301.264; D23.101.100;

Online Note: use ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE to search DIFFERENTIATION ANTIGENS, HAIRY CELL LEUKEMIA 1988-91; use ANTIGENS, DIFFERENTIATION to search LEU ANTIGENS 1989 to present; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988

History Note: 88; DIFFERENTIATION ANTIGENS, HAIRY CELL LEUKEMIA was see ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1988-91; LEU ANTIGENS was see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988

Technical Notes: GEN: prefer specific groups & specific differentiation antigens; note X ref LEU ANTIGENS but several specific Leu antigens are also available; DF: ANTIGENS DIFFER